Skip to main content
OpenTrials
Completed

NCT Number: NCT05295576

Effect of Non Surgical Periodontal Therapy on Inflammatory Markers in Chronic Periodontitis Patients

The current study was performed to study levels of Il-17 and Il-18 in aggressive periodontitis patients before and after non surgical periodontal therapy

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Aggressive Periodontitis Mouth Diseases Periodontal Diseases Periodontitis Stomatognathic Diseases

Age range

30 year–60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Future university in Egypt

Cairo, 11835, Egypt

About this study

Background:host defense factors are involved in pathogenesis of chronic periodontitis so, the current study is assessing levels of Il-17 and Il-18 in chronic periodontitis patients versus periodontally healthy controls.

Subjects and methods: Fifty subjects were included; twenty five of them are diagnosed with chronic periodontitis patients and twenty five are periodontally healthy subjects. Probing depth (PD), clinical attachment level (CAL), plaque index (PI) and gingival index (GI) were recorded for all the enrolled subjects. GCF levels of Il-17 and IL-18 were analyzed by enzyme-linked immunosorbent assay (ELISA).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Medically free subjects .
  • both genders .
  • age range between 30 to 60 years old .

Exclusion criteria

  • Subjects with periodontal surgeries in the last 6 months.
  • Subjects with prior use of antibiotics in the last 6 months.
  • Smokers.
  • Pregnant and lactating females were excluded.
  • Lactating females.

Treatment and study plan

Non surgical periodontal therapy

Procedure

Scaling and root planing

Primary outcomes

  1. measure levels of Il-17 and Il-18 in chronic periodontitis patients

    Time frame: Change from Baseline Il-17 andIl-18 at 3 months

    measure levels of Il-17 and Il-18 in GCF of chronic periodontitis patients

Sponsors and collaborators

Lead sponsor

Future University in Egypt

Other

Registry information

Official study title

Effect of Non Surgical Periodontal Therapy on Levels of Il-17 and Il-18 in Chronic Periodontitis Patients Versus Periodontally Healthy Individuals

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Mar 25, 2022
Registry last updated
Mar 25, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.