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OpenTrials
Completed

NCT Number: NCT03561831

Effect of Anaesthesia on ER Stress in Cancer Patients

Investigate the change in endoplasmic reticulum stress after cancer surgery according to different anaesthetics including propofol and sevoflurane.

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Key information

Conditions

Endoplasmic Reticulum Stress

Age range

20 year and older

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Konkuk University Medical Center

Seoul, 05030, South Korea

About this study

We hypothesize propofol and sevoflurane based anesthesia would show different pattern of endoplasmic reticulum stress after cancer surgery in patients with cancer

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients with cancer

Exclusion criteria

  • age under 19 years old
  • allergy history to propofol or sevoflurane
  • history of previous cancer

Treatment and study plan

Propofol

Drug

propofol based anesthesia

Sevoflurane

Drug

sevoflurane based anesthesia

Primary outcomes

  1. Change in endoplasmic reticulum stress

    Time frame: baseline, postoperative 1 hours and 24 hours

    Change in endoplasmic reticulum stress

Sponsors and collaborators

Lead sponsor

Konkuk University Medical Center

Other

Registry information

Official study title

Evaluation the Effects of Anaesthetic Agents on Endoplasmic Reticulum Stress During Cancer Surgery

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
Jun 19, 2018
Registry last updated
Oct 15, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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