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OpenTrials
Completed

NCT Number: NCT04440397

Relationship Between Endoplasmic Reticulum Stress and Pain in Patients With Endometriosis

The correlation between painful symptoms (dysmenorrhea, dysparonia, dysuria, chronic pelvic pain) symptoms and endoplasmic reticulum stress was investigated in 86 patients diagnosed with endometriosis. For this, xbp-1 (x box binding protein-1) level was measured in patients. XBP-1 is an endoplasmic reticulum stress indicator and is known to be involved in pain pathogenesis.

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Key information

Conditions

Endometriosis Endometriosis-related Pain Endoplasmic Reticulum Stress Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Female Urogenital Diseases

Age range

18 year–50 year

Sex eligibility

Female

Study type

Observational

Primary location

Pinar Yalcin Bahat

Istanbul, İ̇stanbul, 34000, Turkey (Türkiye)

About this study

Women between the ages of 18-50 who were diagnosed with endometriosis by surgery and ultrasound, without known rheumatological or metabolic diseases were included in the study. Most of the patients are composed of newly diagnosed patients.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • diagnosed endometriosis with ultrasound or surgery
  • no metabolic diseases
  • no rheumatological diseases

Exclusion criteria

  • Immune modulator, hormonal, anti-inflammatory use history in the last 3 months

Treatment and study plan

xbp-1 - endometriosis patients group

Other

Patients diagnosed with endometriosis by surgery and ultrasound and whose xbp-1 level was examined

Primary outcomes

  1. Evaluation of the correlations between the results of XBP-1 levels and the stages and pain symptoms of endometriosis.

    Time frame: 5 months

Secondary outcomes

  1. serum XBP-1levels in patients wit endometriosis

    Time frame: 5 months

Sponsors and collaborators

Lead sponsor

Kanuni Sultan Suleyman Training and Research Hospital

Other

Registry information

Official study title

Endoplasmic Reticulum Stress and Endometriosis Releated Pain

Important dates

Study start
2020
Primary completion
2020
Study completion
2020
First posted
Jun 19, 2020
Registry last updated
Aug 7, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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