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NCT Number: NCT07115394

EEG Measurements to Capture DBS-induced Electric Potentials

To measure the electric fields induced by DBS (deep brain stimulation) on the scalp and to improve electric field simulations, the investigators will measure EEG (electroencephalography) measurements with high sampling rates (>100 kHz). The investigators hypothesize that we can improve electric field simulations of DBS by validating and calibrating the simulations based on EEG measurements at high sampling rates (>100 kHz).

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Key information

Conditions

Deep Brain Stimulation Parkinson's Disease

Age range

35 year–85 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Provision of written informed consent by the patient
  • Age 35 - 85
  • patient groups: Parkinson's disease, essential tremor, dystonia
  • >3 months after surgery for DBS

Exclusion criteria

none.

Treatment and study plan

EEG recording

Other

EEG will be recorded at high sampling rate

Primary outcomes

  1. Electric potential at the EEG locations

    Time frame: during DBS

    The investigators will extract the DBS pulses from the EEG data and check the distribution of the electric potentials as seen in simulations based on individual MRI and CT images. Parameters of the simulation pipeline (e.g. conductances) will be adjusted so that the simulation models fit the data.

Study contacts

Contact information is provided by the study sponsor or research team.

Bettina C. Schwab, PhD

CONTACT

[email protected]

+49 40 7410 26907

Thomas Keizers

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

Universitätsklinikum Hamburg-Eppendorf

Other

Collaborators

  • University of Twente

Registry information

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Aug 11, 2025
Registry last updated
Aug 21, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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