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OpenTrials
Completed

NCT Number: NCT06339073

CT-based Model for Predicting Prolonged Weaning in Patients With Abdominal Trauma

Critically ill patients often require tracheal intubation for mechanical ventilation, and timely weaning is crucial for airway management and reducing complications. However, there is currently a lack of an effective tool to predict weaning time in critically ill patients. This retrospective study established an effective nomogram model for predicting the time of weaning from mechanical ventilation in abdominal trauma patients by considering multiple perspectives. The model has been validated and demonstrated good performance in terms of discrimination, calibration, and clinical utility. Moreover, the model can effectively predict the prognosis of critically ill patients. The findings of this study have important implications for guiding respiratory management in clinically critically ill patients, particularly trauma patients.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

the General Surgical Department of Jinling Hospital

Nanjing, Jiangsu, 210002, China

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • (1) with information on survival status and time;
  • (2) aged 18-80 years;
  • (3) admitted to ICU;
  • (4) with abdominal CT performed within 1-week post-trauma;
  • (5) use of mechanical ventilation.

Exclusion criteria

  • (1) low-quality CT images;
  • (2) history of mental illness.

Treatment and study plan

Mechanical ventilation

Device

Abdominal trauma patients were treated with mechanical ventilation according to their conditions.

Primary outcomes

  1. Prolonged mechanical ventilation

    Time frame: through whole hospitalization of each participant, an average of 25 days

    Prolonged mechanical ventilation was defined as length of mechanical ventilation >7 days

Sponsors and collaborators

Lead sponsor

Jinling Hospital, China

Other

Registry information

Official study title

CT-based Model for Predicting Prolonged Weaning From Mechanical Ventilation in Patients With Abdominal Trauma: a Retrospective Cohort Study

Important dates

Study start
2023
Primary completion
2023
Study completion
2024
First posted
Apr 1, 2024
Registry last updated
Apr 1, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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