Skip to main content
OpenTrials
Completed

NCT Number: NCT01090206

Correlation Between Vitamin D Status and Bone Mineral Density in Patients With Hemophilia

Study will look at baseline Vitamin D levels, calcium, albumin, liver enzymes, testosterone, osteocalcin, urine N telopeptides, bone mineral density, nutritional assessment and physical activity assessment of boys with hemophilia A or B (ages 2-20 yrs). Patients with low vitamin D levels will receive therapeutic doses of Vitamin D. At end of one year follow up studies will be repeated.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Hemophilia A Avitaminosis Blood Coagulation Disorders Blood Coagulation Disorders, Inherited Coagulation Protein Disorders Congenital, Hereditary, and Neonatal Diseases and Abnormalities Deficiency Diseases Genetic Diseases, Inborn Genetic Diseases, X-Linked Hematologic Diseases Hemic and Lymphatic Diseases Hemophilia B Hemorrhagic Disorders Malnutrition Nutrition Disorders Nutritional and Metabolic Diseases Vitamin D Deficiency

Age range

2 year–21 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Virginia Commonwealth University Health System

Richmond, Virginia, 23298, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • clinical diagnosis of Hemophilia A or B
  • ages 2-21 years

Exclusion criteria

  • therapeutic vitamin D or calcium supplementation within 3 months of study entry

Treatment and study plan

Vitamin D and calcium

Dietary Supplement

Doses will be based on Vitamin D levels

Primary outcomes

  1. Correlate between Vitamin D deficiency, low bone mass and lack of weight bearing physical activity

    Time frame: 1year

Secondary outcomes

  1. Determine bone mass (density) in hemophilia patients

    Time frame: 1 yr

  2. establish dose and duration of treatment with vitamin D

    Time frame: 1 yr

Sponsors and collaborators

Lead sponsor

Virginia Commonwealth University

Other

Collaborators

  • CSL Behring

Registry information

Important dates

Study start
2010
Primary completion
2013
Study completion
2015
First posted
Mar 19, 2010
Registry last updated
Apr 29, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.