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Completed

NCT Number: NCT03388684

Conjoined Twins: a Report of Four Cases.

The present study aims to report our experience in conjoined twin separation surgery in Assuit university and pediatric hospital, Assiut university, Assiut, Egypt over a period of 20 years.

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Key information

About this study

A conjoined twin is a subset of monozygotic twin gestation. It's a rare phenomenon with an incidence of 1 in 50,000 to 1:100,000 births with the higher incidence in Africa and Southwest Asia. Based on the terminology proposed by Spencer and colleagues, conjoined twins are classified according to the most prominent site of conjunction into three major groups; First, twins with a ventral union; [cephalopagus (head), thoracopagus (Thorax), omphalopagus (Abdomen) and ischiopagus (pelvis)]. Second; twins with a dorsal union; [pygopagus (sacrum), rachipagus (spine, back) and craniopagus (cranium)] and lastly; twins with a lateral union that is referred to as parapagus (side). Depending on the aspect of the embryonic disc, the most common types are thoracopagus (19%).

Surgical separation of conjoined twins is extremely challenging taking in consideration the high perioperative risk. The low incidence of such surgeries and anatomical variations in each type of conjoined twins makes each separation surgery a unique experience.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • conjoined twins
  • symmetrical or
  • asymmetrical.

Exclusion criteria

  • conjoined twins incompatible with life
  • conjoined twins with decapitating medical illness.

Treatment and study plan

Conjoined twin separation surgery

Procedure

This study included 4 case reports on conjoined twins (CT), 2 male and three female patients; 3 of them were parasitic and one was conjoined. We operated upon 2 parasitic and one conjoined. The 1st case died preoperatively.

Other names: CT Separation

Primary outcomes

  1. Success of the conjoined twin separation surgery

    Time frame: For each case was the 1 week survival

    The operative details of the separation surgery were written in details and the separation process was showen in pictures.

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Acronym: CT

Important dates

Study start
2000
Primary completion
2017
Study completion
2017
First posted
Jan 3, 2018
Registry last updated
Jun 25, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.