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NCT Number: NCT07383636

Comparison of Plaque Removal Efficacy of Different Toothbrushes in Clear Aligner Patients

This study aims to compare the effectiveness of manual and powered toothbrushes in removing dental plaque in patients undergoing clear aligner orthodontic treatment.

Clear aligner treatment uses attachments bonded to teeth to facilitate tooth movement. These attachments may increase plaque accumulation around the tooth surface. Poor plaque control can lead to dental caries and periodontal problems.

In this study, patients receiving clear aligner treatment will brush their teeth using either a manual or a powered toothbrush. Dental plaque levels around attachments will be evaluated before and after brushing using a modified plaque index.

The results of this study may help determine whether one type of toothbrush is more effective than the other in maintaining oral hygiene during clear aligner therapy.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Mersin University, Faculty of Dentistry, Department of Orthodontics

Mersin, 33150, Turkey (Türkiye)

About this study

Dental plaque is a complex biofilm and a primary etiological factor in the development of dental caries and periodontal diseases. Orthodontic treatments may increase plaque accumulation due to the presence of attachments bonded to the tooth surface.

Clear aligner therapy has become increasingly popular due to its esthetic and removable nature. However, attachments used during treatment may compromise oral hygiene by promoting plaque retention, particularly in the gingival region.

This study is designed to evaluate and compare the plaque removal effectiveness of manual and powered toothbrushes in patients undergoing clear aligner orthodontic treatment.

A total of 14 patients receiving clear aligner therapy will be randomly assigned to either a manual toothbrush group or a powered toothbrush group. Dental plaque accumulation around attachments will be assessed before brushing (T0) and after a standardized two-minute brushing period (T1) using the Modified Plaque Index adapted for orthodontic patients.

Plaque scores will be evaluated at multiple tooth surfaces (mesial, distal, occlusal, and gingival) and analyzed both on a patient-based and tooth-based level. Attachments will also be categorized as conventional or optimized, and plaque reduction will be compared between attachment types.

The findings of this study are expected to provide evidence regarding the effectiveness of different toothbrush types in maintaining oral hygiene in patients treated with clear aligners.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥ 18 years
  • Undergoing orthodontic treatment with clear aligners
  • Presence of bonded attachments on teeth
  • No known systemic diseases
  • Not using any regular systemic medications
  • Right-handed individuals (actively using the right hand)

Exclusion criteria

  • Age < 18 years
  • Absence of attachments on teeth
  • Presence of any systemic disease
  • Regular use of systemic medications
  • Left-handed or ambidextrous individuals

Treatment and study plan

Manual toothbrush

Device

Use of a manual toothbrush for plaque removal in patients undergoing clear aligner therapy.

Other names: TePe Select™ Medium

Powered toothbrush

Device

Use of a powered toothbrush for plaque removal in patients undergoing clear aligner therapy.

Other names: Oral-B iO 9, Electric toothbrush

Primary outcomes

  1. Change in Modified Plaque Index (MPI) Score After Toothbrushing

    Time frame: Immediately before and immediately after a single 2-minute toothbrushing session

    The primary outcome is the change in dental plaque accumulation measured using the Modified Plaque Index (MPI). Plaque scores will be recorded immediately before toothbrushing (T0) and immediately after a standardized 2-minute toothbrushing session (T1). The difference between T0 and T1 MPI scores will be calculated to assess plaque removal effectiveness.

Sponsors and collaborators

Lead sponsor

Mersin University

Other

Registry information

Official study title

Comparison of the Plaque Removal Efficacy of Manual and Powered Toothbrushes in Patients Undergoing Clear Aligner Therapy

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Feb 3, 2026
Registry last updated
Feb 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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