Department of Cardiothoracic Surgery, Perfusion. Sahlgrenska University Hospital.
Gothenburg, Västra Götaland County, 41345, Sweden
NCT Number: NCT05820828
The goal of this single center prospective controlled observational and interventional trial is to investigate and compare origin of air emboli when different venous cannulation methods is used in patients undergoing cardiac surgery with extracorporeal circulation.
40 consecutive elective patients will be included in two groups, depending on the procedure requiring bicaval or cavoatrial cannulation. After assorted into respective group, patients will be block randomized (five groups consisting of eight patients each) to either intervention group (low venous reservoir volume, 200-300 mL) or control group (venous reservoir volume > 300 mL).
Primary endpoint is to investigate if the amount of air emboli passing through the oxygenator to the arterial line differs between bicaval and cavoatrial venous cannulation during extracorporeal circulation. Secondary endpoints are the relative difference in amount air emboli between the groups, if there is any correlation between the amount of air in venous line and the amount of air passing through the oxygenator to the arterial line during extracorporeal circulation, and if difference is seen on the amount of air passing through the oxygenator depending on the level of volume in the venous reservoir.
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Notify Me18 year and older
All sexes
Interventional
Not applicable
Gothenburg, Västra Götaland County, 41345, Sweden
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Volume control in venous reservoir during extracorporeal circulation.
Time frame: 1 day (During extracorporeal circulation)
Bubble counter measurements
Time frame: 1 day (During extracorporeal circulation)
Bubble counter measurements
Time frame: 1 day (During extracorporeal circulation)
Bubble counter measurements
Time frame: 1 day (During extracorporeal circulation)
Bubble counter measurements
Time frame: 1 day (During extracorporeal circulation)
Bubble counter measurements
Petronella Torild
Other
Does Venous Cannulation Method Affect Air Embolic Load to the Patient During Extracorporeal Circulation?
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