Body Weight and Carb Metabolism

Inclusion criteria

• Able to cycle continuously for 2 hours at a moderate intensity
• VO2max of between 40-75 mL/kg/min
• Fat-mass index (determined by dual energy x-ray absorptiometry) < 5.5 kg·m-2

Exclusion criteria

• Diagnosed disorders of the gastrointestinal tract (e.g. crohn's, colitis etc.)
• People following a low-carbohydrate, high-fat diet
• Pregnant or lactating
• Diagnosed cardiovascular disease
• Possible symptoms of cardiovascular disease
• Diagnosis of diabetes of any type
• Hypercholesterolaemia (total cholesterol ≥ 6.2 mmol/L
• Hypertension (systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg)
• Current smoker
• Family history of coronary artery disease (first-degree relative <60 years)
• Prevalence of vascular disease
• Autonomic neuropathy
• Kidney disease
• Diagnosed pulmonary disease (e.g. chronic obstructive pulmonary disease, asthma, interstitial lung disease or cystic fibrosis)
• Blood borne disease or infection
• Osteoporosis
• Osteoarthritis
• Blood clotting disorders
• Food intolerances/allergies (these may not specifically exclude you- please talk to the investigator)
• Sensitivity or allergy to anaesthetic