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Active, Not Recruiting

NCT Number: NCT07646665

Exogenous Carbohydrate Oxidation During High Intensity Exercise

The aim of the current project is to assess exogenous glucose oxidation rates during exercise at moderate and high intensity.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Exercise Metabolism

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Bath

Bath, BA2 7AY, United Kingdom

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Endurance trained
  • Aged 18 to 65 years

Exclusion criteria

  • Contraindications to exercise
  • Unable to complete 2 hours of continuous cycling

Treatment and study plan

Glucose

Other

Glucose ingestion at 90 g/h labelled with U13C glucose

Primary outcomes

  1. Total exogenous glucose oxidation rate

    Time frame: Measured over 120 mins

    Total exogenous glucose oxidation rate (g/h)

Secondary outcomes

  1. Exogenous glucose oxidation rate during moderate intensity exercise

    Time frame: 90 minutes

    Exogenous glucose oxidation rate during moderate intensity exercise (g/h)

  2. Exogenous glucose oxidation rate during high intensity exercise

    Time frame: 30 minutes

    Exogenous glucose oxidation rate during high intensity exercise (g/h)

Other outcomes

  1. Blood glucose concentrations

    Time frame: 120 minutes

    Blood glucose concentrations (mmol/L)

  2. Blood lactate concentrations

    Time frame: 120 minutes

    Blood lactate concentrations (mmol/L)

  3. Blood bicarbonate concentrations

    Time frame: 120 minutes

    Blood bicarbonate concentrations (mmol/L

  4. Blood pCO2

    Time frame: 120 minutes

    Blood pCO2 (mmHg)

  5. Oxygen consumption rate

    Time frame: 120 minutes

    Oxygen consumption rate (L/min)

  6. Carbon dioxide production rate

    Time frame: 120 minutes

    Carbon dioxide production rate (L/min)

Sponsors and collaborators

Lead sponsor

University of Bath

Other

Registry information

Acronym: Glucose ox

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jun 15, 2026
Registry last updated
Jul 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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