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Completed

NCT Number: NCT06206577

Autogenous Grafts for Anterior Maxillary Horizontal Ridge Augmentation

The aim of the study was to compare efficacy of autogenous onlay and inlay grafts for anterior maxillary horizontal ridge augmentation.

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Key information

Age range

20 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Mansoura U

Al Mansurah, Egypt

About this study

Autogenous block graft has been used as onlay thin cortical shell and cortico-cancellous particles. The thin cortical shell acts as an autogenous biological membrane that will resist resorption and stabilize the small pieces of particulate bone. The bone block is screwed-in at a distance from the recipient site by means of titanium bone screws, and then the free space under the shell is filled with the particulate bone.

The resultant augmentation somehow resembles an iliac graft, with thick internal cancellous bone and a thin external cortical layer. This leads to an ideal graft, with a high regenerative capacity comparable to iliac bone and a stable regenerated volume with optimum osseointegration potential close to that of mandibular block grafts.

Interpositional grafts have been successfully established in restoring vertical bone height . However much less evidence is present on its use for horizontal augmentation. It is the purpose of this study to assess the efficacy of autogenous onlay corticocancellous block grafts for anterior maxillary horizontal ridge augmentation as compared to onlay block grafts.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with missing upper anterior tooth / teeth with horizontal ridge dimension range from 2 to 5 mm (measured 2mm below alveolar crest).
  • Adequate vertical height.
  • Having good oral hygiene.
  • being healthy, with no systemic diseases that might contraindicate receiving a dental implant
  • Patients were able to comply with the follow-up and maintenance program

Exclusion criteria

  • Presence of local infection or lesions at site of interest.
  • Dental history of bruxism, or other parafunctional habits.
  • Uncooperative patients.
  • Current chemotherapy or radiotherapy.
  • Patients with aggressive periodontal disease

Treatment and study plan

Horizontal ridge augmentation by symphyseal bone block placed and fixed buccally as onlay graft

Procedure

autogenous bone block harvested from chin area using piezosurgery and fixed buccally in deficient area with fixation screws

Horizontal ridge augmentation by symphyseal bone block interpositioned in space created between buccal and lingual cortex as inlay graft

Procedure

autogenous bone block harvested from chin area using piezosurgery and fixed in bone split created at deficient area with fixation screws

Primary outcomes

  1. horizontal ridge augmentation

    Time frame: 12 months

    CBCT to assess bone gain in mm

Sponsors and collaborators

Lead sponsor

Mansoura University

Other

Registry information

Official study title

Autogenous Inlay Versus Onlay Grafts for Anterior Maxillary Horizontal Ridge Augmentation

Important dates

Study start
2020
Primary completion
2022
Study completion
2023
First posted
Jan 16, 2024
Registry last updated
Jan 16, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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