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NCT Number: NCT07540429

ADOLESCENTS IMAGING USING fMRI: Feasibility Study

Impaired social cognition and cognitive control associated with borderline personality disorder (BPD) remain less explored. Recent Franco-Canadian study, has shown the feasibility of a neuroimaging tests in Quebec adolescents with BPD. This study aims to increase knowledgements related to neural correlates of BPD and clinical disorders.

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Key information

Conditions

Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group Absence of Pathology on the CBCL and Ab-DIB for the Healthy Control Group All Participants Were Euthymic at the Time of Task Administration Borderline Personality Disorder Diagnosis of ADHD Using the KSADS-PL for the ADHD Group Mental Disorders Personality Disorders

Age range

12 year–17 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Female adolescents meeting DIB-R criteria for BPD group
  • Female adolescents meeting kSADS-PL for ADHD group
  • Female adolescents without any psychologic disorders

Exclusion criteria

  • Any medical history with head trauma, chronic neurologic disease, any contraindications for fRMI, claustrophobia or pregnancy.

Treatment and study plan

Functional Magnetic Resonance Imaging (fMRI)

Diagnostic Test

Investigators used fMRI to compare patterns of regional brain activation between three groups of adolescents girls: Six female adolescents meeting criteria for BPD, 6 female adolescents meeting criteria of ADHD and 6 female adolescents without psychiatric disorder were recruited.

Primary outcomes

  1. MRI-Acquired Activation Mapping

    Time frame: 2 years

    Establishment of activation maps by statistical analysis of local signal variations to locate functional regions essential to motor skills and language.

Secondary outcomes

  1. Feasibility of this study

    Time frame: 2 years

    Pilot feasibility study with a small sample size

Study contacts

Contact information is provided by the study sponsor or research team.

Jean Marc GUILE, Professor

CONTACT

[email protected]

MICHAEL MONET, PhD

CONTACT

[email protected]

0322534612

Sponsors and collaborators

Lead sponsor

Etablissement Public de la Sante Mentale de la Somme

Network

Collaborators

  • Centre Hospitalier Universitaire, Amiens

Registry information

Official study title

Feasibility Study Using Functional Magnetic Resonance Imaging (fMRI) on Bordeline Personality Disorders in Adolescents

Acronym: ADO IMAGE

Important dates

Study start
2024
Primary completion
2027
Study completion
2027
First posted
Apr 20, 2026
Registry last updated
Apr 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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