CHU Montpellier
Montpellier, 34000, France
Location status: Recruiting
NCT Number: NCT07337889
This study aims to explore a novel conceptualization of Borderline Personality Disorder (BPD) as a "Relationship Use Disorder." The research proposes that BPD shares key features with behavioral addictions, specifically addiction to interpersonal relationships. The study builds upon previous findings suggesting that individuals with BPD experience intense emotional dysregulation, including negative self-perception, shame, and a compulsive need for external validation. This addiction to relationships, much like substance use disorders, is thought to contribute significantly to the difficulties faced by these individuals, including interpersonal conflicts, self-destructive behaviors, and emotional instability.
The study seeks to demonstrate that the relational difficulties central to BPD meet the diagnostic criteria for addiction as defined by the DSM-5. It will also explore how these relational struggles are mediated by dysfunctional self-perception and whether they are linked to behaviors such as compulsive sexual behaviors (CSBD) or suicidal tendencies. Additionally, the research will investigate the relationship between addiction to relationships and neurobiological factors, including endorphin levels, in individuals with BPD compared to those with bipolar disorder and healthy controls. The hypothesis is that individuals with BPD will exhibit higher levels of relationship addiction, with this addiction being tied to their perception of self-worth and emotional experiences in relationships.
This innovative approach aims to refine the understanding of BPD, reduce stigma, and improve treatment strategies by providing scientific evidence supporting the conceptualization of BPD as a "Relationship Use Disorder."
Interested in participating?
Request Info18 year–45 year
All sexes
Interventional
Not applicable
Montpellier, 34000, France
Location status: Recruiting
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Questionnaire adapted from the 'Substance Use Disorders' section of the DSM-5: Disorder related to the use of close relationships
Time frame: Measured at baseline
Using the experimental relationship-use questionnaire based on the DSM-5 Substance Use Disorder items among patients with Borderline Personality Disorder (BPD) without Bipolar Disorder (BD), those with BD without BPD, and healthy controls.
Time frame: Measured at baseline
Administer the Function Acquisition Speed Test (FAST) to measure how quickly individuals learn associations between stimuli and responses, focusing on emotional biases related to self (e.g., feelings of unworthiness, ridicule) and others (e.g., dependency, validation). The aim is to assess the intensity of emotional biases in BPD patients compared to BD patients and healthy controls.
Time frame: Measured at baseline
After viewing an educational video explaining Borderline Personality Disorder (BPD) as relational addiction, assess how participants perceive the alignment of their personal experiences with BPD traits, using a Visual Analogue Scale (VAS) ranging from 0 to 10.
Time frame: Measured at baseline
Using the Love Addiction Inventory (LAI), a 24-item self-report scale, to measure symptoms of love addiction. Participants rate their responses on a 5-point Likert scale, with higher scores indicating greater levels of love addiction symptoms, among patients with Borderline Personality Disorder (BPD) without Bipolar Disorder (BD), those with BD without BPD.
Time frame: Measured at baseline
valuate the correlation between beta-endorphin levels and the dimension of relational addiction among patients with BPD, BD, and healthy controls
Time frame: Measured at baseline
Assessing dysfunctional self-perception and its associated indicators-including feelings of emptiness - among BPD group, BD group and HC group, using :
Time frame: Measured at baseline
Assessing dysfunctional self-perception and its associated indicators-including self-esteem-among BPD group, BD group and HC group, using :
Time frame: Measured at baseline
Assessing dysfunctional self-perception and its associated indicators-including shame,-among BPD group, BD group and HC group, using :
Time frame: Measured at baseline
Assessing dysfunctional self-perception and its associated indicators-including shame,-among BPD group, BD group and HC group, using :
Time frame: Measured at baseline
Assessing the impact of painful relational experiences, focusing on rejection sensitivity, among patients diagnosed with Borderline Personality Disorder (BPD) without Bipolar Disorder (BD), those with BD without BPD, and healthy controls (HC), using :
Time frame: Measured at baseline
Assessing the impact of painful relational experiences, focusing on loneliness, among patients diagnosed with Borderline Personality Disorder (BPD) without Bipolar Disorder (BD), those with BD without BPD, and healthy controls (HC), using :
Time frame: Measured at baseline
Assessing the impact of painful relational experiences, focusing on attachment styles, among patients diagnosed with Borderline Personality Disorder (BPD) without Bipolar Disorder (BD), those with BD without BPD, and healthy controls (HC), using :
Time frame: Measured at baseline
Assessing the severity of compulsive sexual behaviors (CSBD) among patients with Borderline Personality Disorder (BPD) without Bipolar Disorder (BD), those with BD without BPD, and healthy controls (HC), using :
Time frame: Measured at baseline
Assessment of Non-Relational Addictive Behaviors in Patients with Borderline Personality Disorder (BPD), Bipolar Disorder (BD), and Healthy Controls (HC), using substance use disorder criteria.
Participants will be screened for a range of substances (e.g., alcohol, opioids, stimulants) and will be asked about the frequency, quantity, and impact of substance use in their life.
Time frame: Measured at baseline
Assessment of Suicidal Tendencies in Patients with Borderline Personality Disorder (BPD), Bipolar Disorder (BD), and Healthy Controls (HC), using :
University Hospital, Montpellier
Other
Acronym: TLUR
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT04296604
Attention Deficit Disorder with Hyperactivity, Attention Deficit Hyperactivity Disorder
Boston, Massachusetts, United States
View Trial DetailsNCT05698589
Autism Spectrum Disorder, Behavior
Bordeaux, France
View Trial DetailsNCT07199166
Borderline Personality Disorder, Borderline Personality Disorder (BPD)
View Trial DetailsNCT04244786
Behavior, Behavioral Symptoms
New York, United States
View Trial Details