Connecticut Mental Health Center
New Haven, Connecticut, 06519, United States
Location status: Recruiting
NCT Number: NCT06446765
The purpose of this study is to test the ability of mindfulness-based real time functional magnetic resonance imaging (fMRI) neurofeedback (mbNF) to increase the benefits of evidence-based psychotherapy for adults with Borderline Personality Disorder (BPD).
Interested in participating?
Request Info18 year–60 year
All sexes
Interventional
Phase 2
New Haven, Connecticut, 06519, United States
Location status: Recruiting
The focus of this study is Aim 1.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Eligibility will be determined by study personnel.
Participants will complete one session of mindfulness-based fMRI neurofeedback prior to 20 weeks of remote online weekly DBT skills group.
Participants will complete one session of control fMRI neurofeedback prior to 20 weeks of remote online weekly DBT skills group.
Time frame: From baseline (immediately before neurofeedback) to immediately after neurofeedback on the same day
Defined as within-DMN connectivity as the resting state seed-based connectivity between core nodes of medial prefrontal cortex (mPFC) and posterior cingulate cortex (PCC). Change = post-NF within-DMN connectivity - pre-NF within-DMN connectivity.
Time frame: From baseline (immediately before neurofeedback) to immediately after neurofeedback on the same day
Defined as DMN-FPCN anticorrelation as the fMRI seed-based connectivity from mPFC to dorsolateral prefrontal cortex (dlPFC)). Change = post-NF mPFC-dlPFC anticorrelation - pre-NF mPFC-dlPFC anticorrelation
Time frame: From baseline (immediately before neurofeedback) to immediately after neurofeedback on the same day
The State Mindfulness Scale (SMS) is a validated self-reported 21 item instrument assessing state mindfulness over the past 15 minutes. Possible scores range from 21 (not mindful) to 105 (very mindful).
Contact information is provided by the study sponsor or research team.
Yale University
Other
Mindfulness-based Neurofeedback to Augment Dialectical Behavior Therapy (DBT) for Adults With Borderline Personality Disorder (Aim 1)
Acronym: MIND-BPD
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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