Skip to main content
OpenTrials
Completed

NCT Number: NCT02125812

Adjunctive Systemic Administration of Moxifloxacin in the Treatment of Aggressive Periodontitis

The adjunctive use of systemically administered antibiotics has been shown to provide a better clinical outcome, particularly in terms of probing depth (PD) reduction and attachment-level gain than SRP in subjects with Aggressive Periodontitis.

The overall objective of this study is to evaluate the clinical and microbiological efficacy of moxifloxacin as an adjunct to scaling and root planing versus scaling and root planing over placebo in the treatment of aggressive periodontitis.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Aggressive Periodontitis Mouth Diseases Periodontal Diseases Periodontitis Stomatognathic Diseases

Age range

15 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Faculty of Dentistry

Departamento de Antioquia, Medellin, Colombia

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • under 30 years old and systemically healthy, with at least 20 teeth present. Be willing to participate in the study which is corroborated by signing the informed consent form.

Commit to attend post-therapeutic controls and stop drinking alcohol during the time of ingestion of antibiotics.

Exclusion criteria

  • Subjects in whom are contraindicated or with hypersensitivity to quinolones - Subjects who have undergone periodontal, surgical or mechanical antibiotic therapy six months before the start of the study according to interrogation.

Women in pregnancy or lactation, corroborated with previous medical history and medical consultation.

Treatment and study plan

scaling and systemic moxifloxacin

Other

scaling and root planing (SRP) combined with systemic moxifloxacin

Scaling and root planing

Other

scaling and root planing

Primary outcomes

  1. probing depth

    Time frame: six months

Secondary outcomes

  1. clinical attachment level and probing depth

    Time frame: 6 moths

Sponsors and collaborators

Lead sponsor

Facultad Nacional de Salud Publica

Other

Collaborators

  • Universidad de Antioquia

Registry information

Official study title

Adjunctive Systemic Administration of Moxifloxacin in the Treatment of Aggressive Periodontitis: Double-blind Controlled Clinical Trial

Important dates

Study start
2011
Primary completion
2014
Study completion
2014
First posted
Apr 29, 2014
Registry last updated
Jun 2, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.