ICON-Salt Lake City
Salt Lake City, Utah, 84124, United States
NCT Number: NCT06433661
The purpose of this study is to evaluate the effect of food on the amount of etavopivat in the bloodstream of healthy participants. Participants will take a single oral dose of etavopivat following a high-fat meal (i.e. fed) and on an empty stomach (i.e fasted) on two separate occasions.The study will last up to 50 days (including screening).
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Notify Me18 year–55 year
All sexes
Interventional
Phase 1
Salt Lake City, Utah, 84124, United States
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Participants will receive single dose of oral Etavopivat in each treatment period.
Time frame: From 0 to 120 hours after IMP administration (V2/V6)
Measured as hours nanograms per milliliter (h*ng/mL).
Time frame: From 0 to 120 hours after IMP administration (V2/V6)
Measured as nanograms per milliliter (ng/mL).
Time frame: From 0 to 120 hours after IMP administration (V2/V6)
Measured as hours nanograms per milliliter (h*ng/ml).
Time frame: From 0 to 120 hours after IMP administration (V2/V6)
Measured as hours.
Time frame: From 0 to 120 hours after IMP administration (V2/V6)
Measured as hours.
Time frame: From 0 to 120 hours after IMP administration (V2/V6)
Measured as liter per hours (L/h).
Time frame: From 0 to 120 hours after IMP administration (V2/V6)
Measured as liters (L).
Time frame: From IMP administration on day 1 to completion of the end of study visit (V10)
Measured as count of events.
Novo Nordisk A/S
Industry
A Single-centre, Open-label, Randomised, Single-dose, Crossover Study to Evaluate the Effect of Food on the Pharmacokinetics of Etavopivat in Healthy Participants
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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