A New Prognostic Scoring System for Spo… | Clinical Trial

Key information

Conditions

Rupture, Spontaneous Adenocarcinoma Carcinoma Carcinoma, Hepatocellular Digestive System Diseases Digestive System Neoplasms Liver Diseases Liver Neoplasms Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Glandular and Epithelial Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms

Age range

15 year–75 year

Sex eligibility

All sexes

Study type

Observational

About this study

There has been no special prognostic scoring system for HCC patients with tumor rupture in the literature. In this work, we obtained all survival risk factors of ruptured HCC patients who underwent partial hepatectomy using multivariable Cox regression analysis. Furthermore, we develop and validate a new postoperative scoring system for patients with spontaneous HCC rupture based on the these results.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Received partial hepatectomy; with Child A or B liver function.

Exclusion criteria

Without complete data；loss of follow-up; had reveived repeated transcatheter arterial chemoembolization before rupture; received non-radical resection.

Treatment and study plan

liver resection

Procedure

Partial hepatectomy comprised single or multiple hepatic resections aiming at excising all visible malignant tissue.

Primary outcomes

Overall survival

Time frame: 3 years

Overall survival after partial hepatectomy

Secondary outcomes

Disease-free survival

Time frame: 3 years

Recurrence-free survival after partial hepatectomy

Sponsors and collaborators

Lead sponsor

Huazhong University of Science and Technology

Other

Registry information

Official study title

A New Prognostic Scoring System for Spontaneous Ruptured Hepatocellular Carcinoma: A Retrospective Study

Important dates

Study start: 2005
Primary completion: 2015
Study completion: 2017
First posted: Apr 20, 2018
Registry last updated: Apr 20, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed