Skip to main content
OpenTrials
Completed

NCT Number: NCT03534843

A Comparison Between Child-Pugh and Albumin-Bilirubin Scores

To compare Child-Pugh and Albumin-Bilirubin scores in patients with spontaneous rupture of hepatocellular carcinoma

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Rupture, Spontaneous Adenocarcinoma Carcinoma Carcinoma, Hepatocellular Digestive System Diseases Digestive System Neoplasms Hepatic Impairment Hepatocellular Carcinoma Liver Diseases Liver Neoplasms Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Glandular and Epithelial Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Rupture Liver

Age range

15 year–76 year

Sex eligibility

All sexes

Study type

Observational

About this study

To compare Child-Pugh and Albumin-Bilirubin scores in patients with spontaneous rupture of hepatocellular carcinoma. And to determine which is better in predicting long-term survival and short-term survival.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Be diagnosed as hepatocellular carcinoma pathologically; had a tumor rupture confirmed by Intraperitoneal exploration or clinical signs and symptoms in combination with imaging examination.

Exclusion criteria

  • Be diagnosed as not hepatocellular carcinoma pathologically；had repeated transcatheter arterial chemoembolization(TACE) or a long history (more than 1 year) of cancer treatment; loss of follow up or without complete data.

Treatment and study plan

liver resection

Procedure

Liver resection was comprised of single or multiple liver resections aiming to excise all macroscopic tumors.

Transcatheter arterial embolization

Other

Transcatheter arterial embolization or transcatheter arterial chemoembolization can localize the bleeding point and provide interventional embolization.

Primary outcomes

  1. Overall survival of all patients

    Time frame: 5 years

    Overall survival of all patients among different Child-Pugh and albumin-bilirubin scores

Secondary outcomes

  1. Short-term mortality of all patients

    Time frame: Ninety days

    Ninety-day mortality of all patients among different Child-Pugh and albumin-bilirubin scores

  2. Short-term mortality of surgical subgroup

    Time frame: Ninety days

    Ninety-day mortality of the surgical subgroup among different Child-Pugh and albumin-bilirubin scores

  3. Short-term mortality of non-surgical subgroup

    Time frame: Ninety days

    Ninety-day mortality of the non-surgical subgroup among different Child-Pugh and albumin-bilirubin scores

Sponsors and collaborators

Lead sponsor

Huazhong University of Science and Technology

Other

Registry information

Official study title

A Comparison Between Child-Pugh and Albumin-Bilirubin Scores in Patients With Spontaneous Rupture of Hepatocellular Carcinoma: A Retrospective Study

Important dates

Study start
2005
Primary completion
2015
Study completion
2018
First posted
May 23, 2018
Registry last updated
May 29, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.