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Completed

NCT Number: NCT06112769

A Correlation Study of Internal Jugular Vein Variability Under Deep Inhalation and Propofol-induced Hypotension

The correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

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Key information

Age range

60 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Affiliated Hospital of Jiaxing University

Jiaxing, Zhejiang, 314000, China

About this study

  • Ultrasound records at least one quiet breathing cycle and one deep inhalation cycle to calculate IJVV
  • Propofol was infused target-controlled at 4 μg/ml, and changes in arterial blood pressure within 3 minutes of propofol induction were observed.
  • Aim to conduct a prospective observational study to evaluate the correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age over 60 years
  • American Society of Anesthesiology (ASA) status Ⅱ-Ⅲ
  • Surgery with radial artery puncture
  • Propofol induction

Exclusion criteria

  • BMI≥30kg/m2
  • People with short necks;
  • Previous hypotension (systolic blood pressure <90mmHg or mean arterial pressure <65mmHg)
  • Previous poorly controlled hypertension
  • Cardiac insufficiency , EF value<50%
  • Upper limb deep vein thrombosis
  • History of radiotherapy or neck surgery
  • Inability to maintain a supine position for necessary measurements
  • Mechanical ventilation status or inability to take deep breaths patients
  • gastrointestinal surgery
  • patients allergic to propofol.

Treatment and study plan

Primary outcomes

  1. IJVV during deep inhalation

    Time frame: 1 year

    IJVV (%) = (diamax - diamin)/[(diamax + diamin)/2] × 100

Sponsors and collaborators

Lead sponsor

Affiliated Hospital of Jiaxing University

Other

Registry information

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Nov 1, 2023
Registry last updated
Mar 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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