Study of Alpha-blockers Alone During Preoperative Preparation in Patients With Pheochromocytoma

Study of the relationship between hemodynamic stability and preoperative intravenous rehydration in patients with pheochromocytoma

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Key information

Conditions

Adrenal Pheochromocytoma Hemodynamic Neoplasms Neoplasms by Histologic Type Neoplasms, Germ Cell and Embryonal Neoplasms, Nerve Tissue Neuroectodermal Tumors Neuroendocrine Tumors Paraganglioma Pheochromocytoma

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

All patients were subclassified into either the hemodynamic stability group (HS group) or the hemodynamic instability group (HU group) according to whether intraoperative hemodynamic instability occurred. Differences in data between the two groups were examined, and the risk factors for intraoperative hemodynamic instability were analyzed using logistic regression.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Clinical diagnosis of adrenal pheochromocytoma Must be able to swallow tablets

Exclusion criteria

Bilateral or multiple pheochromocytomas. Ectopic pheochromocytoma

Treatment and study plan

Abandonment of intravenous volume expansion during preoperative preparation in patients with pheochromocytoma

Drug

Abandonment of intravenous volume expansion with alpha-blockers during preoperative preparation in patients with pheochromocytoma

Primary outcomes

intraoperative mean arterial pressure

Time frame: During surgery

an intraoperative mean arterial pressure <60 mmHg is considered to be hemodynamically unstable

Sponsors and collaborators

Lead sponsor

Kunwu Yan,MM

Other

Registry information

Official study title

Clinical Study of Abandonment of Intravenous Volume Expansion After Preoperative Use of α-blockers in Patients With Adrenal Pheochromocytoma

Important dates

Study start: 2014
Primary completion: 2022
Study completion: 2022
First posted: Apr 7, 2023
Registry last updated: Apr 7, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed