Studying Cognition in SPG4 | Clinical Trial

Key information

Conditions

Cognitive Impairment Cognition Disorders Cognitive Dysfunction Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Genetic Diseases, Inborn Hereditary Sensory and Motor Neuropathy Hereditary Spastic Paraplegia Heredodegenerative Disorders, Nervous System Mental Disorders Nervous System Diseases Nervous System Malformations Neurocognitive Disorders Neurodegenerative Diseases Neuromuscular Diseases Peripheral Nervous System Diseases Polyneuropathies Spastic Paraplegia, Hereditary

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University Hospital Tübingen, Center for Neurology

Tübingen, 72076, Germany

About this study

Comparing the cognitive levels of patients with SPG4 mutations to healthy controls by using the CANTAB® and MoCA.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patient with SPG4 with known SPAST-Mutation (patient group) or healthy control
Age 18 to 70 years
Written, informed consent

Exclusion criteria

Lack of ability for a written, informed consent
Presence of gait disorder or other neurological condition (for healthy controls)

Treatment and study plan

CANTAB

Diagnostic Test

CANTAB Cognitive Assessment (tablet based cognitive testing from CAMCOG)

MoCA

Diagnostic Test

Montreal cognitive assessment (MOCA) in German

Primary outcomes

Identifying cognitive affected domains by using CANTAB

Time frame: day 1

Number of SPG4 patients with affections in the examined cognitive domains by using CANTAB

Sponsors and collaborators

Lead sponsor

University Hospital Tuebingen

Other

Registry information

Official study title

Studying Cognition in SPG4 Compared to Healthy Controls

Important dates

Study start: 2017
Primary completion: 2017
Study completion: 2017
First posted: Apr 7, 2017
Registry last updated: Aug 28, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed