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NCT Number: NCT06949878

21% Hydrochloric Acid Based Versus 6.6 % Hydrochloric Based Micro Abrasive Kit in Management of Patients With Mild to Moderate Fluorosis

compare the clinical performance of different concentrations of hydrochloric acid based as micro abrasive kits in management of patients with mild to moderate fluorosis over 6month follow up .

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Key information

About this study

microabrasion is a permanent cosmetic dentistry treatment indeed to preserve the health of all part of any defect in enamel.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients who wanted to change the appearance of their stained teeth Males or females. Patients with three or more stained incisors and canines Patients willing and able to attend periodic follow-up visits Patient concerning with oral health. Co-operative patients who show interest to participate in the study.

Exclusion criteria

Patients with known allergic or adverse reaction to the tested materials. Smoking habit Patients having Poor oral hygiene Patients with special health care needs or any systemic disease that may affect treatment Patients participating in other dental studies. Patients suffering from white spot lesion, hypoplasia, amelogenesis imperfecta, dentinogenesis imperfecta, or badly broken and missing teeth due to MIH.

Participants who had a history of dental bleaching.

Treatment and study plan

Antivet

Drug

Complete stain removal from the Enamel-Use a compact cotton swab (3 mm) to apply Antivet solution (Dental Continental, México)to the stained dental piece according to manufacturer's instructions.-Replace the swab as it becomes stained and continue until the stain is removed. " This may take 1-5 minutes per tooth, but do not exceed 15 minutes in total. " - We will keep the tooth moist during the process for effective results and avoid reusing stained cotton swab.-Then we will apply the neutralizing solution to the tooth with a brush or micro brush, ensuring it reaches the gingival margin. Leave it on for 2 minutes.-Once the antivet solution is neutralized, rinse the area and remove the rubber dam.

opalustre

Drug

Complete stain removal from the Enamel. Product will be applied to the surface with a 1 mm thick layer; ten applications of 60s to help penetration of the gel into the enamel.- Using an abrasive rubber cup (OpalCup™ Ultradent) in contra-angle low-speed handpiece at low revolution.- Then will be rinsed with injectable water for 30 seconds between each application.

Primary outcomes

  1. Clinical assessment of treatment success

    Time frame: T( Time ) T0(base line )=Immediately , T1 = 3 Months , T2 = 6 Month

    Enamel discoloration or texture by Spectrophotometer Vita EasyShade When totally removed of fluorotic white spots = success & when stains doesn't removed and surface irregular = failure

Secondary outcomes

  1. Clinical evaluation of Sensitivity

    Time frame: Time frame : T( Time ) T0(base line )=Immediately , T1 = 3 Months , T2 = 6 Month

    Patient reported outcome measures by visual analog scale (VAS) Is used to describe sensitivity by patient themselves in scores as ( o : no sensitivity) ( 10 : highly sensitive )

  2. Patient satisfaction with the Treatment.

    Time frame: Time frame : T( Time ) T0(base line )=Immediately , T1 = 3 Months , T2 = 6 Month

    Patient reported outcome measures by 4-point Likert scale used to describe patient satisfaction with treatment as [(a) "yes, very satisfied", (b) "yes, mostly satisfied", (c) "less satisfied", (d) "not at all satisfied"].

Study contacts

Contact information is provided by the study sponsor or research team.

Rawda H AbdElAziz, Lecturer

CONTACT

[email protected]

0020201001097200

Yaqeen A Abdel-Razeq, Master's candidate

CONTACT

[email protected]

0020201018769392 ext. 0201121159913

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Clinical Evaluation of Different Concentrations of Hydrochloric Acid Based as Micro Abrasive Kits in Management of Patients With Mild to Moderate Fluorosis (A 6month Randomized Clinical Trial)

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Apr 29, 2025
Registry last updated
Apr 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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