NCT00005766
- Conditions
- Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
- Locations
-
- University of Vermont Burlington, Vermont, United States
Clinical trial condition
TDP-43 Proteinopathies
Explore clinical trials studying TDP-43 Proteinopathies. Study availability and eligibility vary by location and protocol.
870 public trials
211 recruiting studies
TDP-43 Proteinopathies trial results
Active, Not Recruiting
Acamprosate in C9orf72 Hexanucleotide Repeat Expansion Amyotrophic Lateral Sclerosis (ACALS)
NCT07204977
- Conditions
- Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Frontotemporal Dementia With Motor Neuron Disease, +9 more
- Locations
-
- National Institutes of Health Clinical Center Bethesda, Maryland, United States
Active, Not Recruiting
HEALEY ALS Platform Trial - Master Protocol
NCT04297683
- Conditions
- Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
- Locations
-
- Barrow Neurological Institute Phoenix, Arizona, United States
- Mayo Clinic Scottsdale Scottsdale, Arizona, United States
- University of Arkansas for Medical Sciences Little Rock, Arkansas, United States
- UC San Diego La Jolla, California, United States
Active, Not Recruiting
FUSION: A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of ION363 in Amyotrophic Lateral Sclerosis Participants With Fused in Sarcoma Mutations (FUS-ALS)
NCT04768972
- Conditions
- Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
- Locations
-
- University of California San Diego La Jolla, California, United States
- Stanford University Medical Center Palo Alto, California, United States
- Johns Hopkins University Baltimore, Maryland, United States
- Massachusetts General Hospital Boston, Massachusetts, United States
Active, Not Recruiting
HEALEY ALS Platform Trial - Regimen I NUZ-001
NCT07410806
- Conditions
- Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Central Nervous System Diseases, +9 more
- Locations
-
- Healey Center for ALS at Massachusetts General Hospital Boston, Massachusetts, United States
Active, Not Recruiting
Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)
NCT04408625
- Conditions
- Brain Diseases, Central Nervous System Diseases, Dementia, +10 more
- Locations
-
- k2 Medical Research-Maitland Maitland, Florida, United States
- PPD Phase 1 Clinic, 100 West Gore Street, Suite 202 Orlando, Florida, United States
- Lahey Hospital & Medical Center, 41 Burlington Mall Road Burlington, Massachusetts, United States
- Hospital of the University of Pennsylvania, 3 West Gates Building, 3400 Spruce Street Philadelphia, Pennsylvania, United States
Active, Not Recruiting
Intravenous Immunoglobulin (IVIG) and Blood-Brain Barrier Disruption in Amyotrophic Lateral Sclerosis (ALS)
NCT07193953
- Conditions
- ALS, Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, +9 more
- Locations
-
- Sunnybrook Health Sciences Centre Toronto, Ontario, Canada
Active, Not Recruiting
Personalized Antisense Oligonucleotide for a Single Participant With CHCHD10 ALS
NCT06977451
- Conditions
- Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
- Locations
-
- Columbia University, Irving Medical Center New York, United States
Active, Not Recruiting
Personalized Antisense Oligonucleotide Therapy for A Single Participant With CHCHD10 ALS
NCT06392126
- Conditions
- Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
- Locations
-
- Mayo Clinic Jacksonville, Florida, United States
Active, Not Recruiting
A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS)
NCT06643481
- Conditions
- Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Central Nervous System Diseases, +9 more
- Locations
-
- University of California San Diego La Jolla, California, United States
- Loma Linda University Health Loma Linda, California, United States
- Keck Medical Center USC Los Angeles, California, United States
- UC San Francisco Medical Center San Francisco, California, United States