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Clinical trial condition

Retinal Degeneration

Explore clinical trials studying Retinal Degeneration. Study availability and eligibility vary by location and protocol.

94 public trials 13 recruiting studies
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Retinal Degeneration trial results

Active, Not Recruiting

Pivotal 1 Study of ABBV-RGX-314 (Also Known as RGX-314) Gene Therapy Administered Via Subretinal Delivery One Time in Participants With nAMD

NCT04704921

Conditions
AMD, CNV, Choroid Diseases, +18 more
Locations
  • Retinal Research Institute /ID# 256019 Phoenix, Arizona, United States
  • Barnet Dulaney Perkins Eye Center - Sun City /ID# 256055 Sun City, Arizona, United States
  • University of Arkansas for Medical Sciences /ID# 271290 Little Rock, Arkansas, United States
  • Retina Vitreous Assoc Med Grp /ID# 256299 Beverly Hills, California, United States
View all 89 locations
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Active, Not Recruiting

A Clinical Trial Evaluating the Safety and Efficacy of a Single Subretinal Injection of AGTC-501 in Participants With XLRP

NCT04850118

Conditions
Eye Diseases, Eye Diseases, Hereditary, Retinal Degeneration, +2 more
Locations
  • Retina Macula Institute of Arizona Scottsdale, Arizona, United States
  • Children's Hospital Los Angeles Los Angeles, California, United States
  • University of Florida Health Jacksonville, Department of Ophthalmology Jacksonville, Florida, United States
  • Bascom Palmer Eye Institute- University of Miami Miami, Florida, United States
View all 25 locations
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Active, Not Recruiting

Dose-escalation Study to Evaluate the Safety and Tolerability of GS030 in Subjects With Retinitis Pigmentosa

NCT03326336

Conditions
Cone-Rod Dystrophies, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, +7 more
Locations
  • UPMC Eye Center Pittsburgh, Pennsylvania, United States
  • Centre Hospitalier National d'Ophtalmologie (CHNP) des Quinze-Vingts Paris, France
  • Moorfields Eye Hospital NHS Foundation Trust, 162 City Road London, United Kingdom
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Active, Not Recruiting

Long-term Study of ADVM-022 in Neovascular (Wet) AMD [OPTIC-EXT]

NCT04645212

Conditions
Blindness, Choroid Diseases, Choroidal Neovascularization, +18 more
Locations
  • Adverum Clinical Site Bakersfield, California, United States
  • Adverum Clinical Site Beverly Hills, California, United States
  • Adverum Clinical Site Lakewood, Colorado, United States
  • Adverum Clinical Site Deerfield Beach, Florida, United States
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Active, Not Recruiting

Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F

NCT04765345

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Deafness, Autosomal Recessive 23, Eye Diseases, +6 more
Locations
  • University of California, San Francisco San Francisco, California, United States
  • The Johns Hopkins Wilmer Eye Institute Baltimore, Maryland, United States
  • Duke University, Duke Eye Center Durham, North Carolina, United States
  • Hospital for Sick Children Toronto, Ontario, Canada
View Trial Details
Active, Not Recruiting

NG101 AAV Gene Therapy in Subjects With Wet Age-Related Macular Degeneration

NCT05984927

Conditions
Age-Related Macular Degeneration, Choroid Diseases, Choroidal Neovascularization, +11 more
Locations
  • Cincinnati Eye Institute Cincinnati, Ohio, United States
  • Retina Consultants of Texas Bellaire, Texas, United States
  • Vancouver Coastal Health Research Institute Vancouver, British Columbia, Canada
  • Sunnybrook Ophthalmology and Vision Services Toronto, Ontario, Canada
View Trial Details
Active, Not Recruiting

CNS10-NPC for the Treatment of RP

NCT04284293

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Eye Diseases, Hereditary, +5 more
Locations
  • Retina-Vitreous Associates Medical Group Beverly Hills, California, United States
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Active, Not Recruiting

Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study

NCT05797896

Conditions
Anetoderma, Connective Tissue Diseases, Dry Age-related Macular Degeneration, +11 more
Locations
  • Global Research Management Glendale, California, United States
  • Northern California Retina Vitreous Associates Mountain View, California, United States
  • Midwest Eye Institute Carmel, Indiana, United States
  • Mid Atlantic Retina Specialists Hagerstown, Maryland, United States
View all 22 locations
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