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Clinical trial condition

Pyruvate Kinase Deficiency of Red Cells

Explore clinical trials studying Pyruvate Kinase Deficiency of Red Cells. Study availability and eligibility vary by location and protocol.

15 public trials 1 recruiting study
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Pyruvate Kinase Deficiency of Red Cells trial results

Enrolling by invitation

A Study to Provide Access to Mitapivat for Participants Who Previously Participated in an Agios-Sponsored Mitapivat Study

NCT05777993

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +10 more
Locations
  • McMaster Centre for Transfusion Medicine McMaster University Hamilton, Ontario, Canada
  • Tohoku University Hospital Sendai, Miyagi, Japan
  • Kyoto Katsura Hospital Kyoto, Japan
  • Toho University - Omori Medical Center Ōta-ku, Japan
View all 23 locations
View Trial Details
Active, not recruiting

Pyruvate Kinase Deficiency Global Longitudinal Registry

NCT03481738

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +7 more
Locations
  • Phoenix Childrens Hospital Phoenix, Arizona, United States
  • Arkansas Children's Hospital Little Rock, Arkansas, United States
  • University of Arkansas for Medical Sciences Little Rock, Arkansas, United States
  • Children's Hospital of Orange County Orange, California, United States
View all 52 locations
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Active, not recruiting

A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Not Regularly Transfused, Followed by a 5-Year Extension Period

NCT05175105

Conditions
Anemia, Hematologic Diseases, Hemic and Lymphatic Diseases, +5 more
Locations
  • Stanford Medicine Palo Alto, California, United States
  • Children's Hospital Colorado Aurora, Colorado, United States
  • Children's Healthcare of Atlanta - Emory Atlanta, Georgia, United States
  • UChicago Medicine Chicago, Illinois, United States
View all 19 locations
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Active, not recruiting

A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Regularly Transfused, Followed by a 5-Year Extension Period

NCT05144256

Conditions
Anemia, Hematologic Diseases, Hemic and Lymphatic Diseases, +5 more
Locations
  • Phoenix Children's Hospital Phoenix, Arizona, United States
  • Stanford Medicine Palo Alto, California, United States
  • Children's Healthcare of Atlanta - Emory Atlanta, Georgia, United States
  • Boston Children's Hospital Boston, Massachusetts, United States
View all 22 locations
View Trial Details
Completed

A Study of AG-348 in Adult Participants With Pyruvate Kinase (PK) Deficiency

NCT02476916

Conditions
Anemia, Anemia, Hemolytic, Hematologic Diseases, +3 more
Locations
  • Stanford University Palo Alto, California, United States
  • Boston Children's Hospital Boston, Massachusetts, United States
  • Wayne State University School of Medicine - Children's Hospital of Michigan Detroit, Michigan, United States
  • New York Presbyterian Hospital- Weil Cornell Medical College New York, United States
View all 13 locations
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Completed

Extension Study of AG-348 in Adult Participants With Pyruvate Kinase Deficiency Previously Enrolled in AG-348-006 or AG348-C-007

NCT03853798

Conditions
Pyruvate Kinase Deficiency, Pyruvate Kinase Deficiency of Red Cells
Locations
  • Phoenix Children's Hospital Phoenix, Arizona, United States
  • UCSF Benioff Children's Hospital, Oakland Oakland, California, United States
  • Emory-Children's Center Atlanta, Georgia, United States
  • Indiana Hemophilia & Thrombosis Center Inc. Indianapolis, Indiana, United States
View all 42 locations
View Trial Details
Completed

Gene Therapy for Pyruvate Kinase Deficiency (PKD)

NCT04105166

Conditions
Anemia, Anemia, Hemolytic, Hematologic Diseases, +3 more
Locations
  • Stanford University Stanford, California, United States
  • Hospital Infantil Universitario Niño Jesús Madrid, Spain
  • Hospital Universitario Fundación Jiménez Díaz Madrid, Spain
View Trial Details

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