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Clinical trial condition

Proteostasis Deficiencies

Explore clinical trials studying Proteostasis Deficiencies. Study availability and eligibility vary by location and protocol.

1,350 public trials 353 recruiting studies
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Proteostasis Deficiencies trial results

Active, Not Recruiting

Phenotype, Genotype & Biomarkers in ALS and Related Disorders

NCT02327845

Conditions
Amyotrophic Lateral Sclerosis, Brain Diseases, Central Nervous System Diseases, +28 more
Locations
  • Stanford University Palo Alto, California, United States
  • University of California San Diego (UCSD) San Diego, California, United States
  • California Pacific Medical Center (CPMC) San Francisco, California, United States
  • University of Miami Miami, Florida, United States
View all 15 locations
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Active, Not Recruiting

Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or Refractory Light Chain Amyloidosis

NCT04847453

Conditions
Amyloidosis, Immune System Diseases, Immunoglobulin Light-chain Amyloidosis, +11 more
Locations
  • City of Hope Comprehensive Cancer Center Duarte, California, United States
  • University of California Davis Comprehensive Cancer Center Sacramento, California, United States
  • Emory University Hospital/Winship Cancer Institute Atlanta, Georgia, United States
  • Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore, Maryland, United States
View all 16 locations
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Active, Not Recruiting

A Study of PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 Genes

NCT04747431

Conditions
Brain Diseases, C9orf72, Central Nervous System Diseases, +16 more
Locations
  • Michigan Alzheimer's Disease Center Ann Arbor, Michigan, United States
  • University of Pennsylvania Philadelphia, Pennsylvania, United States
  • Vanderbilt University Medical Center Nashville, Tennessee, United States
  • University of Texas at Houston Houston, Texas, United States
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Active, Not Recruiting

A Study Evaluating the Safety and Tolerability of QRL-201 in ALS

NCT05633459

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • Universitaire Ziekenhuizen Leuven (UZ Leuven) Leuven, Belgium
  • University of Calgary Calgary, Alberta, Canada
  • University of Alberta Edmonton, Alberta, Canada
  • Sunnybrook Health Science Centre Toronto, Ontario, Canada
View all 15 locations
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Active, Not Recruiting

Novel MRI Biomarkers for Monitoring Disease Progression in ALS

NCT03362658

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • University of Miami Miami, Florida, United States
  • University of Utah Salt Lake City, Utah, United States
  • University of Calgary / Heritage Medical Research Clinic Calgary, Alberta, Canada
  • University of Alberta Edmonton, Alberta, Canada
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Active, Not Recruiting

A Study of AT-02 in Subjects With Systemic Amyloidosis.

NCT05951049

Conditions
Amyloidosis, Amyloidosis; Systemic, Immune System Diseases, +10 more
Locations
  • Kansas City Kansas City, Kansas, United States
  • Cleveland Clinic Cleveland, Ohio, United States
  • OHSU (Oregon Health & Science University) Portland, Oregon, United States
  • Penn Presbyterian Medical Center Philadelphia, Pennsylvania, United States
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Active, Not Recruiting

A Study to Evaluate the Safety and Pharmacokinetics of Single and Multiple Doses of Prosetin in Healthy Volunteers and Participants With ALS

NCT05279755

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • Massachusetts General Hospital Boston, Massachusetts, United States
  • Worldwide Clinical Trials Early Phase Services San Antonio, Texas, United States
  • The Neuro - Montréal Neurological Institute-Hospital Montreal, Quebec, Canada
  • University Medical Center Utrecht Utrecht, Netherlands
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