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Clinical trial condition

Proteostasis Deficiencies

Explore clinical trials studying Proteostasis Deficiencies. Study availability and eligibility vary by location and protocol.

1,350 public trials 353 recruiting studies
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Proteostasis Deficiencies trial results

Active, Not Recruiting

CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

NCT04136171

Conditions
Amyloidosis, Cardiomyopathies, Cardiovascular Diseases, +5 more
Locations
  • Mayo Clinic - Arizona Phoenix, Arizona, United States
  • Altman Clinical and Translational Research Institute Center for Clinical Research La Jolla, California, United States
  • Cedars-Sinai Medical Center Los Angeles, California, United States
  • University of California, San Francisco (UCSF) - Medical Center San Francisco, California, United States
View all 142 locations
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Active, Not Recruiting

An Observational Study Using Artificial Intelligence (AI) Algorithms on Electrocardiography (ECG), Point-of-care Ultrasound (POCUS), and Transthoracic Echocardiophy (TTE) to Estimate the Under-diagnosis of Transthyretin Amyloid Cardiomyopathy (ATTR-CM) Across a Diverse Range of US Health Systems.

NCT07062848

Conditions
Amyloid Neuropathies, Amyloid Neuropathies, Familial, Amyloidosis, +13 more
Locations
  • University of California - San Francisco (UCSF) Health San Francisco, California, United States
  • Yale New Haven Health System New Haven, Connecticut, United States
  • Henry Ford Health Detroit, Michigan, United States
  • Mount Sinai New York, United States
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Active, Not Recruiting

Regulatory T Cells for Amyotrophic Lateral Sclerosis

NCT05695521

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • Columbia University Irving Medical Center New York, United States
  • Baylor College of Medicine Houston, Texas, United States
  • Michael E. DeBakey Veterans Affairs Medical Center Houston, Texas, United States
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Active, Not Recruiting

Rho Kinase Inhibitor in Amyotrophic Lateral Sclerosis (REAL)

NCT05218668

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • Neuromuscular Research Center Phoenix, Arizona, United States
  • University of Colorado Aurora, Colorado, United States
  • National Jewish Health Denver, Colorado, United States
  • Lakes Research Miami Lakes, Florida, United States
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Active, Not Recruiting

Open-Label Study of AG10 in Patients with Cardiomyopathy

NCT03536767

Conditions
Amyloid Cardiomyopathy, Amyloid Neuropathies, Amyloid Neuropathies, Familial, +13 more
Locations
  • Stanford University Palo Alto, California, United States
  • University of California San Francisco San Francisco, California, United States
  • Yale University New Haven, Connecticut, United States
  • Northwestern University Chicago, Illinois, United States
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