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Clinical trial condition

Proteostasis Deficiencies

Explore clinical trials studying Proteostasis Deficiencies. Study availability and eligibility vary by location and protocol.

1,350 public trials 353 recruiting studies
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Proteostasis Deficiencies trial results

Active, Not Recruiting

Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)

NCT04408625

Conditions
Brain Diseases, Central Nervous System Diseases, Dementia, +10 more
Locations
  • k2 Medical Research-Maitland Maitland, Florida, United States
  • PPD Phase 1 Clinic, 100 West Gore Street, Suite 202 Orlando, Florida, United States
  • Lahey Hospital & Medical Center, 41 Burlington Mall Road Burlington, Massachusetts, United States
  • Hospital of the University of Pennsylvania, 3 West Gates Building, 3400 Spruce Street Philadelphia, Pennsylvania, United States
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Active, Not Recruiting

Isatuximab as Upfront Therapy for the Treatment of High Risk AL Amyloidosis

NCT04754945

Conditions
AL Amyloidosis, Amyloidosis, Immune System Diseases, +10 more
Locations
  • University of California Orange, California, United States
  • Emory University Hospital/Winship Cancer Institute Atlanta, Georgia, United States
  • Emory University Hospital Midtown Atlanta, Georgia, United States
  • Karmanos Cancer Institute Detroit, Michigan, United States
View Trial Details
Active, Not Recruiting

Study of NXC-201 CAR-T in Patients With Light Chain (AL) Amyloidosis

NCT06097832

Conditions
Amyloidosis, Immune System Diseases, Immunoglobulin Light-chain Amyloidosis, +10 more
Locations
  • Sutter Health Alta Bates Berkeley, California, United States
  • City of Hope Duarte, California, United States
  • University of California Los Angeles Los Angeles, California, United States
  • University of California Davis Medical Center Sacramento, California, United States
View all 18 locations
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Active, Not Recruiting

A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS)

NCT06643481

Conditions
Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Central Nervous System Diseases, +9 more
Locations
  • University of California San Diego La Jolla, California, United States
  • Loma Linda University Health Loma Linda, California, United States
  • Keck Medical Center USC Los Angeles, California, United States
  • UC San Francisco Medical Center San Francisco, California, United States
View all 74 locations
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Active, Not Recruiting

Clinical Study of Neflamapimod in Patients With Primary Progressive Aphasia

NCT07033481

Conditions
Aphasia, Aphasia, Primary Progressive, Behavior, +24 more
Locations
  • Northwestern Memorial Hospital Chicago, Illinois, United States
  • Mayo Clinic Rochester, Minnesota, United States
  • Columbia University New York, United States
  • The Ohio State University Columbus, Ohio, United States
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