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Progeria

Clinical trial condition

Progeria

Explore clinical trials studying Progeria. Study availability and eligibility vary by location and protocol.

9 public trials 0 recruiting studies

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Progeria trial results

Not yet recruiting

Creating Stem Cells From a Progeria Patient's Blood to Test Candidate Treatments in the Lab

NCT07803432

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Hutchinson-Gilford Progeria Syndrome, +5 more
Locations: Not specified

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Enrolling by invitation

Phase I/II Trial of Everolimus in Combination With Lonafarnib in Progeria

NCT02579044

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Laminopathies, +4 more
Locations: Boston Children's Hospital Boston, Massachusetts, United States

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Active, not recruiting

Study to Determine Optimal Dose and Evaluate Safety, Tolerability, and Pharmacokinetics of Progerinin in Patients With Hutchinson-Gilford Progeria Syndrome (HGPS)

NCT06775041

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Hutchinson-Gilford Progeria Syndrome, +5 more
Locations: Boston Children's Hospital Boston, Massachusetts, United States

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Completed

Phase I Study of Progerinin in Healthy Volunteers

NCT04512963

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, DNA Repair-Deficiency Disorders, Genetic Diseases, Inborn, +7 more
Locations: PRG S&T Investigational Site Glendale, California, United States

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Completed

Umbilical Cord Blood Transfusion in Progeria Syndrome

NCT03871972

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Hutchinson-Gilford Progeria Syndrome, +5 more
Locations: Bundang CHA Medical Center Seongnam-si, Gyeonggi-do, South Korea

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Completed

Clinical Studies of Progeria

NCT00094393

Conditions: Aging, Premature, Arterial Occlusive Diseases, Arteriosclerosis, +25 more
Locations: National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States

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Completed

Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria

NCT00425607

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Hutchinson-Gilford Syndrome, +5 more
Locations: Children's Hospital Boston Boston, Massachusetts, United States

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Completed

A Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria

NCT00879034

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Hutchinson-Gilford Syndrome, +5 more
Locations: Children's Hospital Boston Boston, Massachusetts, United States

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Completed

Treatment of the Hutchinson-Gilford Progeria Syndrome With a Combination of Pravastatin and Zoledronic Acid

NCT00731016

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Hutchinson-Gilford Progeria Syndrome, +5 more
Locations: Laboratoire de Génétique Moléculaire - Hopital de la Timone Marseille, France

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