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Clinical trial condition

Primary Myelofibrosis

Explore clinical trials studying Primary Myelofibrosis. Study availability and eligibility vary by location and protocol.

453 public trials 89 recruiting studies
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Primary Myelofibrosis trial results

Active, Not Recruiting

Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet Versus Best Available Therapy to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis

NCT04468984

Conditions
Bone Marrow Diseases, Hematologic Diseases, Hemic and Lymphatic Diseases, +4 more
Locations
  • Ironwood Cancer & Res Ctr /ID# 222162 Chandler, Arizona, United States
  • Highlands Oncology Group, PA /ID# 221826 Springdale, Arkansas, United States
  • City of Hope /ID# 218996 Duarte, California, United States
  • Providence - St. Jude Medical Center /ID# 271382 Fullerton, California, United States
View all 229 locations
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Active, Not Recruiting

A Study of Fedratinib in Japanese Subjects With DIPSS (Dynamic International Prognostic Scoring System)- Intermediate or High-risk Primary Myelofibrosis (PMF), Post-polycythemia Vera Myelofibrosis (Post-PV MF), or Post-essential Thrombocythemia Myelofibrosis (Post-ET MF)

NCT04446650

Conditions
Bone Marrow Diseases, Hematologic Diseases, Hemic and Lymphatic Diseases, +2 more
Locations
  • Local Institution - 021 Suwa, Nagano, Japan
  • Local Institution - 001 Bunkyo-ku, Tokyo, Japan
  • Local Institution - 006 Chūō, Yamanashi, Japan
  • Local Institution - 002 Aomori, Japan
View all 21 locations
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Active, Not Recruiting

Safety and Tolerability Study of Oral ABBV-744 Tablet Alone or in Combination With Oral Ruxolitinib Tablet or Oral Navitoclax Tablet in Adult Participants With Myelofibrosis

NCT04454658

Conditions
Bone Marrow Diseases, Hematologic Diseases, Hemic and Lymphatic Diseases, +4 more
Locations
  • University of California, Davis Comprehensive Cancer Center /ID# 221790 Sacramento, California, United States
  • Duplicate_Dartmouth-Hitchcock Medical Center - 1 Medical Center Drive /ID# 224623 Lebanon, New Hampshire, United States
  • Roswell Park Cancer Institute /ID# 222557 Buffalo, New York, United States
  • The Mount Sinai Hospital /ID# 221549 New York, United States
View all 43 locations
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Active, Not Recruiting

Long-term Study Evaluating the Effect of Givinostat in Patients With Chronic Myeloproliferative Neoplasms

NCT01761968

Conditions
Blood Coagulation Disorders, Blood Platelet Disorders, Bone Marrow Diseases, +13 more
Locations
  • Charite Research Organization GmbH Berlin, Germany
  • Universitaetsklinikum Freiburg, Innere Medizin I - Haematologie und Onkologie Freiburg im Breisgau, Germany
  • Azienda Ospedaliero-Universitaria Policlinico Consorziale, Bari Bari, BA, Italy
  • Istituto Tumori Giovanni Paolo II IRCCS Ospedale Oncologico di Bari Bari, BA, Italy
View all 15 locations
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Active, Not Recruiting

Ruxolitinib vs Allogeneic SCT for Patients With Myelofibrosis According to Donor Availability

NCT03333187

Conditions
Bone Marrow Diseases, Bone Marrow Fibrosis, Hematologic Diseases, +3 more
Locations
  • Universitätsklinkum Aachen Aachen, Germany
  • HELIOS Klinikum Berlin-Buch Berlin, Germany
  • Universitätsklinikum Bonn Bonn, Germany
  • Universitätsklinikum Düsseldorf Düsseldorf, Germany
View all 14 locations
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Active, Not Recruiting

A Study Evaluating Safety and Tolerability, and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm

NCT04041050

Conditions
Blood Coagulation Disorders, Blood Platelet Disorders, Bone Marrow Diseases, +22 more
Locations
  • City of Hope /ID# 239769 Duarte, California, United States
  • Providence - St. Jude Medical Center /ID# 242558 Fullerton, California, United States
  • Moores Cancer Center at UC San Diego /ID# 229584 La Jolla, California, United States
  • UCLA /Id# 222784 Los Angeles, California, United States
View all 42 locations
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