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Clinical trial condition

Primary Myelofibrosis

Explore clinical trials studying Primary Myelofibrosis. Study availability and eligibility vary by location and protocol.

453 public trials 89 recruiting studies
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Primary Myelofibrosis trial results

Active, Not Recruiting

A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment

NCT04576156

Conditions
Blood Platelet Disorders, Bone Marrow Diseases, Hematologic Diseases, +6 more
Locations
  • University of California-San Diego/Moores UCSD Cancer Center La Jolla, California, United States
  • UCLA David Geffen School of Medicine Los Angeles, California, United States
  • Smilow Cancer Center at YNHH New Haven, Connecticut, United States
  • BRCR Medical Center Inc Plantation, Florida, United States
View all 144 locations
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Active, Not Recruiting

Study of Stem Cell Transplant vs. Non-Transplant Therapies in High-Risk Myelofibrosis

NCT04217356

Conditions
Bone Marrow Cancer, Bone Marrow Diseases, Bone Marrow Neoplasms, +9 more
Locations
  • Tom Baker Cancer Centre Calgary, Alberta, Canada
  • Cross Cancer Institute Edmonton, Alberta, Canada
  • St. Paul's Hospital Vancouver, British Columbia, Canada
  • Nova Scotia Health Authority Halifax, Nova Scotia, Canada
View Trial Details
Active, Not Recruiting

CINC424A2X01B Rollover Protocol

NCT02386800

Conditions
Acute Myeloid Leukemia, Anemia, Anemia, Hemolytic, +31 more
Locations
  • Novartis Investigative Site Darlinghurst, New South Wales, Australia
  • Novartis Investigative Site Herston, Queensland, Australia
  • Novartis Investigative Site Wooloongabba, Queensland, Australia
  • Novartis Investigative Site Bedford Park, South Australia, Australia
View all 97 locations
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Active, Not Recruiting

A Study to Evaluate Single Agent Selinexor Versus Physician's Choice in Participants With Previously Treated Myelofibrosis

NCT04562870

Conditions
Bone Marrow Diseases, Hematologic Diseases, Hemic and Lymphatic Diseases, +3 more
Locations
  • The Oncology Institute of Hope and Innovation Pasadena, California, United States
  • Rocky Mountain Cancer Centers, LLP Aurora, Colorado, United States
  • Illinois Cancer Specialist Niles, Illinois, United States
  • Texas Oncology - Northeast Texas Tyler, Texas, United States
View all 21 locations
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Active, Not Recruiting

Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia

NCT03289910

Conditions
Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Atypical Chronic Myeloid Leukemia, +32 more
Locations
  • Los Angeles General Medical Center Los Angeles, California, United States
  • USC / Norris Comprehensive Cancer Center Los Angeles, California, United States
  • USC Norris Oncology/Hematology-Newport Beach Newport Beach, California, United States
  • Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore, Maryland, United States
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Active, Not Recruiting

Extended Access of Momelotinib in Adults With Myelofibrosis

NCT03441113

Conditions
Bone Marrow Diseases, Hematologic Diseases, Hemic and Lymphatic Diseases, +6 more
Locations
  • GSK Investigational Site Scottsdale, Arizona, United States
  • GSK Investigational Site Orange, California, United States
  • GSK Investigational Site Stanford, California, United States
  • GSK Investigational Site Aurora, Colorado, United States
View all 112 locations
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Active, Not Recruiting

A Study to Assess the Safety and Tolerability of BMS-986158 Alone and in Combination With Either Ruxolitinib or Fedratinib in Participants With Blood Cancer (Myelofibrosis)

NCT04817007

Conditions
Bone Marrow Diseases, Hematologic Diseases, Hemic and Lymphatic Diseases, +3 more
Locations
  • Local Institution - 0069 Newport Beach, California, United States
  • Local Institution - 0090 Lake Mary, Florida, United States
  • Local Institution - 0043 New Orleans, Louisiana, United States
  • Local Institution - 0038 Worcester, Massachusetts, United States
View all 49 locations
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