Skip to main content
OpenTrials

Clinical trial condition

Porphyrias

Explore clinical trials studying Porphyrias. Study availability and eligibility vary by location and protocol.

25 public trials 0 recruiting studies
Refine in advanced search Browse all conditions

Porphyrias trial results

Enrolling by Invitation

HELIOS: Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Efficacy of DISC-1459 (Bitopertin) in Participants With EPP or XLP

NCT05883748

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Erythropoietic Protoporphyria, +10 more
Locations
  • University of Alabama Hospital Birmingham, Alabama, United States
  • University of California San Francisco San Francisco, California, United States
  • University of Miami Miller School of Medicine Miami, Florida, United States
  • Massachusetts General Hospital Boston, Massachusetts, United States
View all 21 locations
View Trial Details
Completed

Study of Bitopertin to Evaluate the Safety, Tolerability, Efficacy, and PPIX Concentrations in Participants With EPP

NCT05308472

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Erythropoietic Protoporphyria, +10 more
Locations
  • University of Alabama Hospital Birmingham, Alabama, United States
  • University of California San Francisco San Francisco, California, United States
  • University of Miami Miller School of Medicine Miami, Florida, United States
  • Massachusetts General Hospital Boston, Massachusetts, United States
View Trial Details
Completed

ENVISION: A Study to Evaluate the Efficacy and Safety of Givosiran (ALN-AS1) in Patients With Acute Hepatic Porphyrias (AHP)

NCT03338816

Conditions
ALA Dehydratase Deficient Porphyria (ADP), Acute Hepatic Porphyria, Acute Intermittent Porphyria, +17 more
Locations
  • Clinical Trial Site Little Rock, Arkansas, United States
  • Clinical Trial Site San Francisco, California, United States
  • Clinical Trial Site Boston, Massachusetts, United States
  • Clinical Trial Site Ann Arbor, Michigan, United States
View all 36 locations
View Trial Details
Completed

A Study to Evaluate Long-term Safety and Clinical Activity of Givosiran (ALN-AS1) in Patient With Acute Intermittent Porphyria (AIP)

NCT02949830

Conditions
Acute Intermittent Porphyria, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +10 more
Locations
  • Clinical Trial Site San Francisco, California, United States
  • Clinical Trial Site New York, United States
  • Clinical Trial Site Galveston, Texas, United States
  • Clinical Trial Site Stockholm, Sweden
View Trial Details
Completed

EXPLORE: A Natural History Study of Acute Hepatic Porphyria (AHP)

NCT02240784

Conditions
Acute Hepatic Porphyria, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Coproporphyria, +11 more
Locations
  • Clinical Trial Site San Francisco, California, United States
  • Clinical Trial Site Miami, Florida, United States
  • Clinical Trial Site Ann Arbor, Michigan, United States
  • Clinical Trial Site New York, United States
View all 30 locations
View Trial Details
Completed

Oral Iron for Erythropoietic Protoporphyrias

NCT02979249

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, EPP, +14 more
Locations
  • University of Alabama, Birmingham Birmingham, Alabama, United States
  • University of California San Francisco, California, United States
  • Icahn School of Medicine at Mount Sinai New York, United States
  • Wake Forest University Health Sciences Winston-Salem, North Carolina, United States
View Trial Details
Completed

Erythropoietic Protoporphyrias: Studies of the Natural History, Genotype-Phenotype Correlations, and Psychosocial Impact

NCT01688895

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, EPP, +18 more
Locations
  • University of Alabama, Birmingham Birmingham, Alabama, United States
  • University of California, San Francisco San Francisco, California, United States
  • Icahn School of Medicine at Mount Sinai New York, United States
  • Wake Forest University Health Sciences Winston-Salem, North Carolina, United States
View Trial Details

Related conditions