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Clinical trial condition

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Explore clinical trials studying Paroxysmal Nocturnal Hemoglobinuria (PNH). Study availability and eligibility vary by location and protocol.

33 public trials 9 recruiting studies
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Paroxysmal Nocturnal Hemoglobinuria (PNH) trial results

Completed

Study of Efficacy and Safety of Twice Daily Oral LNP023 in Adult PNH Patients With Residual Anemia Despite Anti-C5 Antibody Treatment

NCT04558918

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • City Of Hope National Med Center City of Hope Medical Center Duarte, California, United States
  • Univ Cali Irvine ALS Neuromuscular Orange, California, United States
  • Augusta University Georgia Patient Treatment Augusta, Georgia, United States
  • Levine Cancer Insitute Carolinas Healthcare System Charlotte, North Carolina, United States
View all 39 locations
View Trial Details
Completed

ALXN1210 (Ravulizumab) Versus Eculizumab in Complement Inhibitor Treatment-Naïve Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

NCT02946463

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • Research Site Los Angeles, California, United States
  • Research Site Whittier, California, United States
  • Research Site Fort Worth, Texas, United States
  • Research Site Buenos Aires, Argentina
View all 120 locations
View Trial Details
Completed

Phase 2 Safety and Efficacy Study of Zilucoplan (RA101495) to Treat PNH Patients Who Have an Inadequate Response to Eculizumab

NCT03030183

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • Investigative Site Duarte, California, United States
  • Investigative Site Los Angeles, California, United States
  • Investigative Site Chicago, Illinois, United States
  • Investigative Site Manhasset, New York, United States
View Trial Details
Completed

A Phase I Study to Assess the Safety of Pegcetacoplan (APL-2) as an Add-On to Standard of Care in Subjects With PNH

NCT02264639

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +18 more
Locations
  • University of Southern California Norris Comprehensive Cancer Center Los Angeles, California, United States
  • Lakes Research Miami Lakes, Florida, United States
  • University of Lousiville Louisville, Kentucky, United States
  • John Hopkins Hospital Baltimore, Maryland, United States
View Trial Details

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