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Clinical trial condition

Optic Atrophy, Hereditary, Leber

Explore clinical trials studying Optic Atrophy, Hereditary, Leber. Study availability and eligibility vary by location and protocol.

33 public trials 7 recruiting studies
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Optic Atrophy, Hereditary, Leber trial results

Completed

REALITY LHON Registry

NCT03295071

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Eye Diseases, +13 more
Locations
  • Doheny Eye Center UCLA Pasadena Pasadena, California, United States
  • Emory University Hospital Atlanta, Georgia, United States
  • Massachusetts Eye and Ear Infirmary Boston, Massachusetts, United States
  • Wills Eye Institute Philadelphia, Pennsylvania, United States
View Trial Details
Completed

RESCUE and REVERSE Long-term Follow-up

NCT03406104

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Eye Diseases, +13 more
Locations
  • Doheny Eye Center UCLA Pasadena, California, United States
  • Emory University Hospital Atlanta, Georgia, United States
  • Wills Eye Institute Philadelphia, Pennsylvania, United States
  • CHNO Les Quinze Vingts Paris, France
View Trial Details
Completed

Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation (REVERSE)

NCT02652780

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Eye Diseases, +13 more
Locations
  • Doheny Eye Center, University of California, Los Angeles Los Angeles, California, United States
  • Department of Ophthalmology, Emory University School of Medicine Atlanta, Georgia, United States
  • Neuro Ophthalmologic Associates, Wills Eye Hospital, Thomas Jefferson University Philadelphia, Pennsylvania, United States
  • Centre National Hospitalier d'Ophtalmologie des Quinze-Vingt Paris, France
View Trial Details
Completed

Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation

NCT02652767

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Eye Diseases, +13 more
Locations
  • Doheny Eye Center, University of California, Los Angeles Los Angeles, California, United States
  • Department of Ophthalmology, Emory University School of Medicine Atlanta, Georgia, United States
  • Neuro Ophthalmologic Associates, Wills Eye Hospital, Thomas Jefferson University Philadelphia, Pennsylvania, United States
  • Centre National Hospitalier d'Ophtalmologie des Quinze-VingtCentre National Hospitalier d'Ophtalmologie des Quinze-Vingt Paris, France
View Trial Details
Completed

Open-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease

NCT02023866

Conditions
Brain Diseases, Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, +40 more
Locations
  • University of California at San Diego (UCSD) San Diego, California, United States
  • Stanford University Stanford, California, United States
  • Akron Children's Hospital Akron, Ohio, United States
  • Baylor College of Medicine Houston, Texas, United States
View Trial Details
Completed

Study to Evaluate QR-110 in Leber's Congenital Amaurosis (LCA) Due to the c.2991+1655A>G Mutation (p.Cys998X) in the CEP290 Gene

NCT03140969

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Eye Diseases, +14 more
Locations
  • University of Iowa Iowa City, Iowa, United States
  • Scheie Eye Institute, University of Pennsylvania Philadelphia, Pennsylvania, United States
  • Ghent University Hospital and Ghent University Ghent, Belgium
View Trial Details
Completed

Study to Assess the Efficacy and Safety of Raxone in LHON Patients

NCT02774005

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Eye Diseases, +13 more
Locations
  • Retinal Consultants of Arizona Phoenix, Arizona, United States
  • Palo Alto Medical Foundation Palo Alto, California, United States
  • Stanford Byers Eye Institute Stanford, California, United States
  • University of Colorado Health Eye Center Aurora, Colorado, United States
View all 29 locations
View Trial Details

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