NCT07102394
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cutaneous Neurofibroma, Genetic Diseases, Inborn, +20 more
- Locations
-
- Johns Hopkins University Baltimore, Maryland, United States
Clinical trial condition
NF1
Explore clinical trials studying NF1. Study availability and eligibility vary by location and protocol.
14 public trials
2 recruiting studies
NF1 trial results
Recruiting
Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF).
NCT06159166
- Conditions
- Cutaneous Neurofibroma, Monotherapy, NF1
- Locations
-
- Johns Hopkins Hospital Baltimore, Maryland, United States
Not yet recruiting
Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas
NCT05253131
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Fibrosarcoma, Genetic Diseases, Inborn, +23 more
- Locations
-
- The University of Alabama at Birmingham Birmingham, Alabama, United States
Not yet recruiting
Follow-up Study to Evaluate the Safety and Efficacy of FCN-159 in Pediatric Participants With Neurofibromatosis Type 1
NCT07024394
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +18 more
- Locations
-
- Shanghai Ninth People's Hospital Shanghai, Shanghai Municipality, China
Enrolling by invitation
Developing Biomarkers of Plexiform Tumor Burden in Patients With Neurofibromatosis-Type 1
NCT05238909
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +18 more
- Locations
-
- Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois, United States
Active, not recruiting
AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors
NCT01362803
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +22 more
- Locations
-
- Children's National Medical Center Washington D.C., District of Columbia, United States
- National Institutes of Health Clinical Center Bethesda, Maryland, United States
- Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, United States
- Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States
Active, not recruiting
Interventions for Reading Disabilities in NF1
NCT02964884
- Conditions
- Communication Disorders, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyslexia, +28 more
- Locations
-
- Vanderbilt University Nashville, Tennessee, United States
Active, not recruiting
A Study of Avutometinib for People With Solid Tumor Cancers
NCT06104488
- Conditions
- Brain Diseases, Brain Neoplasms, CNS Tumor, Adult, +34 more
- Locations
-
- Children's Healthcare of Atlanta (Data Collection Only) Atlanta, Georgia, United States
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) New York, United States
Active, not recruiting
FCN-159 in Adult Patients With Symptomatic, Inoperable Neurofibromatosis Type 1-Related Plexiform Neurofibromas
NCT05913037
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +18 more
- Locations
-
- Cancer Hospital Chinese Academy of Medical Sciences Beijing, Beijing Municipality, China
- Chinese Academy of Medical Sciences & Peking Union Medical College Beijing, Beijing Municipality, China
- Plastic Surgery Hospital,Chinese Academy of Medical Sciences Beijing, Beijing Municipality, China
- Nanfang Hospital, Southern Medical University Guangzhou, Guangdong, China
Active, not recruiting
Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Adult and Pediatric Participants With Neurofibromatosis Type 1
NCT04954001
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +18 more
- Locations
-
- Children's Hospital Los Angeles Los Angeles, California, United States
- Principal Investigator Hans Gainesville, Florida, United States
- John Hopkins All Children Hospital St. Petersburg, Florida, United States
- Henry Ford Health System Detroit, Michigan, United States