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Neurofibromatosis 1 (NF1)

Clinical trial condition

Neurofibromatosis 1 (NF1)

Explore clinical trials studying Neurofibromatosis 1 (NF1). Study availability and eligibility vary by location and protocol.

3 public trials 1 recruiting study

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Neurofibromatosis 1 (NF1) trial results

Recruiting

Early Phase Study Evaluating MEK and MDM2 Inhibition in Patients With NF1 and MPNST

NCT06735820

Conditions: Atypical Neurofibroma, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Fibrosarcoma, +24 more
Locations: Children's National Hospital Washington D.C., District of Columbia, United States

UT Southwestern Medical Center Dallas, Texas, United States

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Not Yet Recruiting

Efficacy of Mirdametinib Alone or Combination With Radiotherapy for Germline and Sporadic NF1-Altered High-Grade Glioma

NCT07521657

Conditions: Astrocytoma, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, +21 more
Locations: Childrens of Alabama Birmingham, Alabama, United States

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Active, Not Recruiting

MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

NCT02407405

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +18 more
Locations: National Institutes of Health Clinical Center Bethesda, Maryland, United States

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