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Clinical trial condition

Neurofibromatosis 1

Explore clinical trials studying Neurofibromatosis 1. Study availability and eligibility vary by location and protocol.

57 public trials 13 recruiting studies
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Neurofibromatosis 1 trial results

Active, Not Recruiting

Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas

NCT04924608

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +17 more
Locations
  • Research Site Gainesville, Florida, United States
  • Research Site Rockville, Maryland, United States
  • Research Site St Louis, Missouri, United States
  • Research Site Commack, New York, United States
View all 34 locations
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Active, Not Recruiting

FCN-159 in Adult Patients With Symptomatic, Inoperable Neurofibromatosis Type 1-Related Plexiform Neurofibromas

NCT05913037

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +18 more
Locations
  • Cancer Hospital Chinese Academy of Medical Sciences Beijing, Beijing Municipality, China
  • Chinese Academy of Medical Sciences & Peking Union Medical College Beijing, Beijing Municipality, China
  • Plastic Surgery Hospital,Chinese Academy of Medical Sciences Beijing, Beijing Municipality, China
  • Nanfang Hospital, Southern Medical University Guangzhou, Guangdong, China
View all 15 locations
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Active, Not Recruiting

Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Adult and Pediatric Participants With Neurofibromatosis Type 1

NCT04954001

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +18 more
Locations
  • Children's Hospital Los Angeles Los Angeles, California, United States
  • Principal Investigator Hans Gainesville, Florida, United States
  • John Hopkins All Children Hospital St. Petersburg, Florida, United States
  • Henry Ford Health System Detroit, Michigan, United States
View all 14 locations
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