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Clinical trial condition

Neurofibromatoses

Explore clinical trials studying Neurofibromatoses. Study availability and eligibility vary by location and protocol.

141 public trials 19 recruiting studies
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Neurofibromatoses trial results

Active, Not Recruiting

Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.

NCT03363217

Conditions
Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, +29 more
Locations
  • Alberta Children's Hospital Calgary, Alberta, Canada
  • Children and Women's Health Centre of British Colombia Vancouver, British Columbia, Canada
  • IWK Health Centre Halifax, Nova Scotia, Canada
  • The Hospital for Sick Children Toronto, Ontario, Canada
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Active, Not Recruiting

MElanoma Research Lymph Node Prediction Implementation National_001

NCT04759781

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Cranial Nerve Neoplasms, +30 more
Locations
  • Moffitt Cancer Center Tampa, Florida, United States
  • Emory University School of Medicine Atlanta, Georgia, United States
  • University of Kentucky Lexington, Kentucky, United States
  • University of Louisville Louisville, Kentucky, United States
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Active, Not Recruiting

Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas

NCT04924608

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +17 more
Locations
  • Research Site Gainesville, Florida, United States
  • Research Site Rockville, Maryland, United States
  • Research Site St Louis, Missouri, United States
  • Research Site Commack, New York, United States
View all 34 locations
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Active, Not Recruiting

PASS of Paediatric Patients Initiating Selumetinib

NCT05388370

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +14 more
Locations
  • Research Site Vienna, Austria
  • Research Site Amiens, France
  • Research Site Angers, France
  • Research Site Bordeaux, France
View all 46 locations
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Active, Not Recruiting

Study of Aspirin in Patients With Vestibular Schwannoma

NCT03079999

Conditions
Acoustic Neuroma, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, +29 more
Locations
  • Stanford Otolaryngology/HNS Stanford, California, United States
  • University of Miami Miami, Florida, United States
  • Massachusetts Eye and Ear Boston, Massachusetts, United States
  • Mayo Clinic Rochester, Minnesota, United States
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Active, Not Recruiting

FCN-159 in Adult Patients With Symptomatic, Inoperable Neurofibromatosis Type 1-Related Plexiform Neurofibromas

NCT05913037

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +18 more
Locations
  • Cancer Hospital Chinese Academy of Medical Sciences Beijing, Beijing Municipality, China
  • Chinese Academy of Medical Sciences & Peking Union Medical College Beijing, Beijing Municipality, China
  • Plastic Surgery Hospital,Chinese Academy of Medical Sciences Beijing, Beijing Municipality, China
  • Nanfang Hospital, Southern Medical University Guangzhou, Guangdong, China
View all 15 locations
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Active, Not Recruiting

Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Adult and Pediatric Participants With Neurofibromatosis Type 1

NCT04954001

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +18 more
Locations
  • Children's Hospital Los Angeles Los Angeles, California, United States
  • Principal Investigator Hans Gainesville, Florida, United States
  • John Hopkins All Children Hospital St. Petersburg, Florida, United States
  • Henry Ford Health System Detroit, Michigan, United States
View all 14 locations
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