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Clinical trial condition

Neurofibroma

Explore clinical trials studying Neurofibroma. Study availability and eligibility vary by location and protocol.

238 public trials 41 recruiting studies
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Neurofibroma trial results

Active, not recruiting

Observational Study to Evaluate the Effect and Safety of Selumetinib in Pediatric Patients With NF1-PNs

NCT06175637

Conditions
Neoplasms, Neoplasms by Histologic Type, Neoplasms, Nerve Tissue, +8 more
Locations
  • Research Site Beijing, Beijing Municipality, China
  • Research Site Chongqing, Chongqing Municipality, China
  • Research Site Lanzhou, Gansu, China
  • Research Site Guangzhou, Guangdong, China
View all 25 locations
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Active, not recruiting

Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma

NCT01089101

Conditions
Astrocytoma, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, +25 more
Locations
  • Children's Hospital Los Angeles Los Angeles, California, United States
  • Lucile Packard Children's Hospital Stanford University Palo Alto, California, United States
  • UCSF Medical Center-Mount Zion San Francisco, California, United States
  • UCSF Medical Center-Parnassus San Francisco, California, United States
View all 17 locations
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Active, not recruiting

Pediatric Long-Term Follow-up and Rollover Study

NCT03975829

Conditions
Anaplastic Astrocytoma, Anaplastic Ganglioglioma, Anaplastic Oligodendroglioma, +62 more
Locations
  • Phoenix Children s Hospital Phoenix, Arizona, United States
  • Childrens National Hospital Washington D.C., District of Columbia, United States
  • Nicklaus Childrens Hospital Miami, Florida, United States
  • Indiana Uni School of Medicine Indianapolis, Indiana, United States
View all 54 locations
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Active, not recruiting

PASS of Paediatric Patients Initiating Selumetinib

NCT05388370

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +14 more
Locations
  • Research Site Vienna, Austria
  • Research Site Amiens, France
  • Research Site Angers, France
  • Research Site Bordeaux, France
View all 46 locations
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Active, not recruiting

Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of Selumetinib in Adolescent Children With Neurofibromatosis Type 1 Related Plexiform Neurofibromas

NCT05101148

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +14 more
Locations
  • Research Site Rochester, Minnesota, United States
  • Research Site Akron, Ohio, United States
  • Research Site Bydgoszcz, Poland
  • Research Site Gdansk, Poland
View Trial Details
Active, not recruiting

Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PN

NCT05309668

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +14 more
Locations
  • Research Site Akron, Ohio, United States
  • Research Site Philadelphia, Pennsylvania, United States
  • Research Site Houston, Texas, United States
  • Research Site Richmond, Virginia, United States
View all 16 locations
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Active, not recruiting

A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

NCT03871257

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +16 more
Locations
  • Children's Hospital of Alabama Birmingham, Alabama, United States
  • Banner Children's at Desert Mesa, Arizona, United States
  • Phoenix Childrens Hospital Phoenix, Arizona, United States
  • Arkansas Children's Hospital Little Rock, Arkansas, United States
View all 132 locations
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Active, not recruiting

Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia

NCT03190915

Conditions
Bone Marrow Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, +22 more
Locations
  • Children's Hospital of Alabama Birmingham, Alabama, United States
  • Phoenix Childrens Hospital Phoenix, Arizona, United States
  • Arkansas Children's Hospital Little Rock, Arkansas, United States
  • Kaiser Permanente Downey Medical Center Downey, California, United States
View all 57 locations
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