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Clinical trial condition

Neoplastic Syndromes, Hereditary

Explore clinical trials studying Neoplastic Syndromes, Hereditary. Study availability and eligibility vary by location and protocol.

869 public trials 154 recruiting studies
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Neoplastic Syndromes, Hereditary trial results

Active, Not Recruiting

Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)

NCT03210714

Conditions
Advanced Malignant Solid Neoplasm, Central Nervous System Neoplasms, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +74 more
Locations
  • Children's Hospital of Alabama Birmingham, Alabama, United States
  • Providence Alaska Medical Center Anchorage, Alaska, United States
  • Banner Children's at Desert Mesa, Arizona, United States
  • Banner University Medical Center - Tucson Tucson, Arizona, United States
View all 116 locations
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Active, Not Recruiting

A Phase IV Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML)

NCT05252585

Conditions
Angiomyolipoma, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +18 more
Locations
  • Novartis Investigative Site Taichung, Taiwan ROC, Taiwan
  • Novartis Investigative Site Taoyuan, Taiwan ROC, Taiwan
  • Novartis Investigative Site Taipei, Taiwan
  • Novartis Investigative Site Taoyuan, Taiwan
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Active, Not Recruiting

Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PN

NCT05309668

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +14 more
Locations
  • Research Site Akron, Ohio, United States
  • Research Site Philadelphia, Pennsylvania, United States
  • Research Site Houston, Texas, United States
  • Research Site Richmond, Virginia, United States
View all 16 locations
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Active, Not Recruiting

Epidyolex® in Lennox Gastaut, Dravet Syndrome and Tuberous Sclerosis Complex: an Observational Study in ITALY

NCT05485831

Conditions
Brain Diseases, Central Nervous System Diseases, Congenital Abnormalities, +25 more
Locations
  • Policlinico Sant'Orsola di Bologna Bologna, Italy
  • NPI AOU Mater Domini Università Magna Graecia Catanzaro, Italy
  • Università degli studi "G. D'annunzio" Chieti Chieti, Italy
  • Azienda Ospedaliera Universitaria Meyer Neurologia Pediatrica Florence, Italy
View all 18 locations
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Active, Not Recruiting

NF-1, Nutraceutical Intervention

NCT05363267

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +13 more
Locations
  • Masonic Cancer Center, University of Minnesota Minneapolis, Minnesota, United States
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Active, Not Recruiting

Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of Selumetinib in Adolescent Children With Neurofibromatosis Type 1 Related Plexiform Neurofibromas

NCT05101148

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +14 more
Locations
  • Research Site Rochester, Minnesota, United States
  • Research Site Akron, Ohio, United States
  • Research Site Bydgoszcz, Poland
  • Research Site Gdansk, Poland
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Active, Not Recruiting

Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma

NCT01089101

Conditions
Astrocytoma, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, +25 more
Locations
  • Children's Hospital Los Angeles Los Angeles, California, United States
  • Lucile Packard Children's Hospital Stanford University Palo Alto, California, United States
  • UCSF Medical Center-Mount Zion San Francisco, California, United States
  • UCSF Medical Center-Parnassus San Francisco, California, United States
View all 17 locations
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