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Clinical trial condition

Myotonia

Explore clinical trials studying Myotonia. Study availability and eligibility vary by location and protocol.

12 public trials 5 recruiting studies
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Myotonia trial results

Recruiting

Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1

NCT07486934

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, DM1, Genetic Diseases, Inborn, +18 more
Locations
  • UCSD - Altman Clinical and Translational Research Institute La Jolla, California, United States
  • Rare Disease Research, LLC Atlanta, Georgia, United States
  • IU Health Neuroscience Center Indianapolis, Indiana, United States
  • Roy Blunt NextGen Precision Health Institute Columbia, Missouri, United States
View all 21 locations
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Recruiting

A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1)

NCT06185764

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +15 more
Locations
  • Stanford Neuromuscular Research San Carlos, California, United States
  • University of Florida Clinical Research Center Gainesville, Florida, United States
  • University of Kansas Medical Center Fairway, Kansas, United States
  • Boston Children's Hospital Boston, Massachusetts, United States
View all 26 locations
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Enrolling by Invitation

Global Open-Label Extension Study of Del-desiran for the Treatment of DM1

NCT07008469

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, DM1, Genetic Diseases, Inborn, +19 more
Locations
  • University of California, Los Angeles (UCLA) Los Angeles, California, United States
  • Stanford University Stanford, California, United States
  • University of Colorado Denver, Colorado, United States
  • University of Florida Gainesville, Florida, United States
View all 35 locations
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Enrolling by Invitation

A Study of Long-term Safety and Efficacy of VX-670 in Participants With Myotonic Dystrophy Type I

NCT06926621

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +15 more
Locations
  • Wesley Research Institute Auchenflower, Australia
  • Neuroscience Clinical Trials Unit, Alfred Brain Melbourne, Australia
  • Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg - Pulmonology Leuven, Belgium
  • Altasciences Montreal Montreal, Canada
View all 13 locations
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Completed

Lamotrigine as Treatment of Myotonia

NCT01939561

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dystrophia Myotonica Type 1, Genetic Diseases, Inborn, +26 more
Locations
  • Copenhagen Neuromuscular Center, department of Neurology, Rigshospitalet Copenhagen, Denmark
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Completed

Effectiveness of Mexiletine for Treating People With Non-Dystrophic Myotonia

NCT00832000

Conditions
Myotonia, Nervous System Diseases, Neurologic Manifestations, +4 more
Locations
  • University of Kansas Medical Center Kansas City, Kansas, United States
  • Brigham & Women's Hospital Boston, Massachusetts, United States
  • University of Rochester School of Medicine & Dentistry Rochester, New York, United States
  • University of Texas Southwestern Medical Center Dallas, Texas, United States
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