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Clinical trial condition

Myelodysplastic Syndromes

Explore clinical trials studying Myelodysplastic Syndromes. Study availability and eligibility vary by location and protocol.

268 public trials 58 recruiting studies
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Myelodysplastic Syndromes trial results

Completed

Study of Safety in Hemolytic Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Treated With Eculizumab

NCT00122304

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +4 more
Locations
  • Norris Comprehensive Cancer Center Los Angeles, California, United States
  • Stanford University Medical Center, Division of Hematology Stanford, California, United States
  • Hartford Hospital, Cancer Clinical Research Office Hartford, Connecticut, United States
  • Cleveland Clinic Florida, Dept. of Clinical Research Weston, Florida, United States
View all 48 locations
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Completed

Study Using Eculizumab in Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients

NCT00122330

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +4 more
Locations
  • City of Hope National Medical Center, Div. of Hematology & Bone Marrow Transplant Duarte, California, United States
  • University of California at Los Angeles Los Angeles, California, United States
  • Scripps Cancer Center San Diego, California, United States
  • Stanford University Medical Center, Division of Hematology Stanford, California, United States
View all 43 locations
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Active, Not Recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors

NCT04432584

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • Carolinas Healthcare System Charlotte, North Carolina, United States
  • Nationwide Children's Hospital Columbus, Ohio, United States
  • Cliniques Universitaires Saint-Luc Brussels, Belgium
  • AZ Delta Campus Westlaan Roeselare, Belgium
View all 80 locations
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Active, Not Recruiting

A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies

NCT05589896

Conditions
Acute Biphenotypic Leukemia, Acute Leukemia, Acute Lymphoblastic Leukemia, +39 more
Locations
  • City of Hope Duarte, California, United States
  • Moffitt Cancer Center Tampa, Florida, United States
  • Emory University - Winship Cancer Institute Atlanta, Georgia, United States
  • Henry Ford Cancer Institute Detroit, Michigan, United States
View Trial Details
Active, Not Recruiting

Long-term Safety and Tolerability of Iptacopan in Patients With Paroxysmal Nocturnal Hemoglobinuria

NCT04747613

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • City Of Hope National Med Center Duarte, California, United States
  • City Of Hope Duarte, California, United States
  • USC Norris Cancer Center Los Angeles, California, United States
  • Univ Cali Irvine ALS Neuromuscular Orange, California, United States
View all 60 locations
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Active, Not Recruiting

A Long-term Safety and Efficacy Study of Danicopan as an Add-on Therapy to Complement Component 5 Inhibitor (C5i) in Participants With PNH

NCT05389449

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +8 more
Locations
  • Research Site Los Angeles, California, United States
  • Research Site Chicago, Illinois, United States
  • Research Site Baltimore, Maryland, United States
  • Research Site Kansas City, Missouri, United States
View all 45 locations
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Active, Not Recruiting

Specified Drug-use Surveillance of Fabhalta Capsules

NCT06606314

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • Novartis Investigative Site Handa, Aichi-ken, Japan
  • Novartis Investigative Site Nagoya, Aichi-ken, Japan
  • Novartis Investigative Site Nagoya, Aichi-ken, Japan
  • Novartis Investigative Site Okazaki, Aichi-ken, Japan
View all 91 locations
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