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Clinical trial condition

Muscular Atrophy, Spinal

Explore clinical trials studying Muscular Atrophy, Spinal. Study availability and eligibility vary by location and protocol.

214 public trials 48 recruiting studies
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Muscular Atrophy, Spinal trial results

Completed

A Study for Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in Nusinersen (ISIS 396443) Investigational Studies

NCT02594124

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • David Geffen School of Medicine at UCLA Los Angeles, California, United States
  • Stanford University School of Medicine Palo Alto, California, United States
  • Children's Hospital Colorado Aurora, Colorado, United States
  • Connecticut Children's Medical Center Hartford, Connecticut, United States
View all 47 locations
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Completed

Safety and Efficacy of Intravenous OAV101 (AVXS-101) in Pediatric Patients With Spinal Muscular Atrophy (SMA)

NCT04851873

Conditions
Atrophy, Bulbo-Spinal Atrophy, X-Linked, Central Nervous System Diseases, +19 more
Locations
  • Novartis Investigative Site Boston, Massachusetts, United States
  • Novartis Investigative Site St Louis, Missouri, United States
  • Novartis Investigative Site Randwick, New South Wales, Australia
  • Novartis Investigative Site Leuven, Belgium
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Completed

Safety and Efficacy of Intravenous OAV101 (AVXS-101) in Pediatric Patients With Spinal Muscular Atrophy (SMA) (OFELIA)

NCT05073133

Conditions
Atrophy, Bulbo-Spinal Atrophy, X-Linked, Central Nervous System Diseases, +18 more
Locations
  • Novartis Investigative Site CABA, Buenos Aires, Argentina
  • Novartis Investigative Site Buenos Aires, Argentina
  • Novartis Investigative Site Belo Horizonte, Minas Gerais, Brazil
  • Novartis Investigative Site Porto Alegre, Rio Grande do Sul, Brazil
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Completed

Safety and Usability of a Robotic Gait Device for Children and Adolescents With Neurological or Neuromuscular Disease in Their Natural Environment

NCT06167954

Conditions
Acquired Brain Injury, Brain Damage, Chronic, Brain Diseases, +13 more
Locations
  • Hospital Universitario Gregorio Marañón Madrid, Spain
  • Hospital Infantil Universitario Niño Jesús-Servicio de Rehabilitación Madrid, Spain
  • Hospital Universitario Niño Jesús-Servicio de Neuro Ortopedia Madrid, Spain
  • Hospital Universitario 12 de Octubre Madrid, Spain
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Completed

Investigate Safety, Tolerability, PK, PD and Efficacy of Risdiplam (RO7034067) in Infants With Type1 Spinal Muscular Atrophy

NCT02913482

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • Stanford University Medical Center Palo Alto, California, United States
  • Ann and Robert H. Lurie Children Hospital of Chicago Chicago, Illinois, United States
  • Boston Childrens Hospital Boston, Massachusetts, United States
  • Columbia University Medical Center; The Neurological Institute of New York New York, United States
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Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Risdiplam (RO7034067) in Type 2 and 3 Spinal Muscular Atrophy (SMA) Participants

NCT02908685

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • Stanford University Medical Center Palo Alto, California, United States
  • Columbia University Medical Center; The Neurological Institute of New York New York, United States
  • UZ Gent Ghent, Belgium
  • UZ Leuven Gasthuisberg Leuven, Belgium
View all 45 locations
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