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Clinical trial condition

Leptomeningeal Metastasis

Explore clinical trials studying Leptomeningeal Metastasis. Study availability and eligibility vary by location and protocol.

45 public trials 19 recruiting studies
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Leptomeningeal Metastasis trial results

Active, Not Recruiting

Intrathecal Dual Checkpoint Inhibitor (PD-1 and CTLA-4) in Combination With Pemetrexed for Leptomeningeal Metastasis

NCT06809530

Conditions
CTLA4, Central Nervous System Neoplasms, Leptomeningeal Metastasis, +9 more
Locations
  • Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine Beijing, Beijing Municipality, China
  • The Affiliated Huizhou Hospital, Guangzhou Medical University Huizhou, Guangdong, China
  • Huizhou First Hospital Affiliated to Guangdong Medical University Huizhou, Guangdong, China
  • Beijing Chest Hospital, Capital Medical University Beijing, China
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Active, Not Recruiting

Intrathecal Combination of Programmed Death-1 (PD-1)/Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4) Bispecific Antibody and Pemetrexed for Leptomeningeal Metastasis

NCT06762080

Conditions
Central Nervous System Neoplasms, Leptomeningeal Metastasis, Meningeal Carcinomatosis, +5 more
Locations
  • The Affiliated Huizhou Hospital, Guangzhou Medical University Huizhou, Guangdong, China
  • Beijing Chest Hospital, Capital Medical University Beijing, China
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Active, Not Recruiting

Immune Checkpoint Inhibitor Combined With Pemetrexed Intrathecal Injection for Leptomeningeal Metastasis From Solid Tumors

NCT06462222

Conditions
Central Nervous System Neoplasms, Leptomeningeal Metastasis, Meningeal Carcinomatosis, +5 more
Locations
  • The Affiliated Huizhou Hospital, Guangzhou Medical University Huizhou, Guangdong, China
  • Huizhou First Hospital Affiliated to Guangdong Medical University Huizhou, Guangdong, China
  • Beijing Chest Hospital, Capital Medical University Beijing, China
  • Cancer Center, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine Beijing, China
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