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Leptomeningeal Metastasis

Clinical trial condition

Leptomeningeal Metastasis

Explore clinical trials studying Leptomeningeal Metastasis. Study availability and eligibility vary by location and protocol.

45 public trials 19 recruiting studies

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Leptomeningeal Metastasis trial results

Not Yet Recruiting

Wearable-Triggered Digital Safety Net for Real-Time Monitoring & Intervention in Leptomeningeal Metastasis

NCT07704034

Conditions: Central Nervous System Neoplasms, Leptomeningeal Metastasis, Meningeal Carcinomatosis, +8 more
Locations: Cleveland Clinic, Case Comprehensive Cancer Center Cleveland, Ohio, United States

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Not Yet Recruiting

Zorifertinib Plus Intra-Ommaya CSF Chemotherapy for Leptomeningeal Progression in NSCLC After Third-Generation EGFR-TKI

NCT07551414

Conditions: Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, +16 more
Locations: National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing, China

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Not Yet Recruiting

A Two-cohort Study of SHR-A1811 in the Treatment of HER2-positive Breast Cancer With Brain Metastases

NCT07177950

Conditions: Brain Diseases, Brain Metastases, Brain Neoplasms, +14 more
Locations: Not specified

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Not Yet Recruiting

AI-Based Ultrasound Prediction Model for Intracranial Pressure and Prognosis in Lung Cancer Patients With Leptomeningeal Metastasis: A Dual-Center Study

NCT07005791

Conditions: Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, +15 more
Locations: Jiangning Hospital Affiliated to Nanjing Medical University Nanjing, Jiangsu, China

Nanjing Drum-tower Hospital Affiliated to Medical College of Nanjing University Nanjing, Jiangsu, China

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Not Yet Recruiting

Double Dose of Third-generation EGFR-TKI Plus Intrathecal Pemetrexed Versus Double Dose of Third-generation EGFR-TKI in Patients With LM Progression Following the Treatment of Routine Dose of Third-generation EGFR-TKI

NCT06441045

Conditions: Central Nervous System Neoplasms, Leptomeningeal Metastasis, Meningeal Carcinomatosis, +5 more
Locations: Gen Lin Fuzhou, Fujian, China

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Completed

Firmonertinib in the Treatment of EGFR(+) NSCLC Patients With Central Nervous System Metastasis

NCT07239102

Conditions: Central Nervous System Metastasis, Central Nervous System Neoplasms, EGFR Positive Non-small Cell Lung Cancer, +7 more
Locations: Li Xiaoyan Beijing, Beijing Municipality, China

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Completed

DS-8201a for trEatment of aBc, BRain Mets, And Her2[+] Disease

NCT04420598

Conditions: Advanced Breast Cancer, Brain Diseases, Brain Metastases, +19 more
Locations: Champalimaud Center for the Unknown Lisbon, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto) Porto, Portugal

Institut Català d'Oncologica ICO Badalona Badalona, Spain

Hospital Universitari Dexeus Barcelona, Spain

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Completed

Study of Osimertinib in Patients with a Lung Cancer with Brain or Leptomeningeal Metastases with EGFR Mutation

NCT04233021

Conditions: Brain Diseases, Brain Metastases, Brain Neoplasms, +11 more
Locations: Centre Hospitalier Aix-Pertuis Aix-en-Provence, France

CHU Amiens - Groupe Hospitalier Sud Amiens, France

Centre Paul Papin Angers, France

Hôpital privé d'Antony Antony, France

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Completed

Study of TY-9591 in Patients With a Lung Cancer With Brain or Leptomeningeal Metastases With EGFR Mutation

NCT05146219

Conditions: Brain Diseases, Brain Metastases, Brain Neoplasms, +11 more
Locations: National Cancer Center/Cancer Hospitial,Chinese Academy of Medical Sciences and Peking Union Medical College Beijing, Beijing Municipality, China

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Completed

Microfluidic Device to Diagnose Leptomeningeal Metastasis in Breast Cancer

NCT02948751

Conditions: Breast Cancer, Breast Diseases, Breast Neoplasms, +10 more
Locations: Columbia University Irving Medical Center New York, United States

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Leptomeningeal Metastasis

Leptomeningeal Metastasis trial results

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