Skip to main content
OpenTrials

Clinical trial condition

Hyperhomocysteinemia

Explore clinical trials studying Hyperhomocysteinemia. Study availability and eligibility vary by location and protocol.

17 public trials 4 recruiting studies
Refine in advanced search Browse all conditions

Hyperhomocysteinemia trial results

Recruiting

Pegtibatinase as a Treatment for Patients With Classical Homocystinuria (HCU) (Also Known as the COMPOSE Study)

NCT03406611

Conditions
Amino Acid Metabolism, Inborn Errors, Brain Diseases, Brain Diseases, Metabolic, +12 more
Locations
  • Travere Investigational Site Aurora, Colorado, United States
  • Travere Investigational Site Miami, Florida, United States
  • Travere Investigational Site Indianapolis, Indiana, United States
  • Travere Investigational Site Portland, Maine, United States
View Trial Details
Recruiting

A Study to Investigate Efficacy and Safety of Pegtibatinase Compared With Placebo in Participants ≥12 to ≤65 Years of Age With Classical Homocystinuria (HCU) Due to Cystathionine Beta Synthase Deficiency Receiving Standard of Care Treatment

NCT06247085

Conditions
Amino Acid Metabolism, Inborn Errors, Brain Diseases, Brain Diseases, Metabolic, +12 more
Locations
  • Phoenix Children's Hospital Phoenix, Arizona, United States
  • Yale University School of Medicine New Haven, Connecticut, United States
  • Emory University Atlanta, Georgia, United States
  • Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois, United States
View all 52 locations
View Trial Details
Recruiting

Natural History Study of Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (ACAPPELLA)

NCT02998710

Conditions
Amino Acid Metabolism, Inborn Errors, Brain Diseases, Brain Diseases, Metabolic, +13 more
Locations
  • Travere Investigational Site - Virtual Site Culver City, California, United States
  • Travere Investigational Site (Enrolling 1 to <5 Year-olds Only) Aurora, Colorado, United States
  • Travere Investigational Site (Enrolling 1 to <5 Year-olds Only) Washington D.C., District of Columbia, United States
  • Travere Investigational Site Atlanta, Georgia, United States
View Trial Details
Enrolling by invitation

A Long-term Extension Study to Assess the Long-term Safety and Efficacy of Pegtibatinase Treatment in Participants ≥5 to ≤65 Years of Age With Classical Homocystinuria (HCU) (ENSEMBLE)

NCT06431893

Conditions
Amino Acid Metabolism, Inborn Errors, Brain Diseases, Brain Diseases, Metabolic, +12 more
Locations
  • Phoenix Children's Hospital Phoenix, Arizona, United States
  • Yale University School of Medicine New Haven, Connecticut, United States
  • Emory University Atlanta, Georgia, United States
  • Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois, United States
View all 52 locations
View Trial Details
Active, not recruiting

Early Check: Expanded Screening in Newborns

NCT03655223

Conditions
17 Alpha-Hydroxylase Deficiency, 3-Hydroxy-3-Methylglutaric Aciduria, 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency, +456 more
Locations
  • RTI International Research Triangle Park, North Carolina, United States
View Trial Details
Completed

Evaluation of the Express Plus Range

NCT05051657

Conditions
Amino Acid Metabolism, Inborn Errors, Brain Diseases, Brain Diseases, Metabolic, +18 more
Locations
  • Royal Belfast Hospital for Sick Children Belfast, United Kingdom
  • Birmingham Women's and Children's Hospital Birmingham, United Kingdom
  • Bristol Royal Hospital for Children Bristol, United Kingdom
  • Greater Glasgow and Clyde NHS Foundation Trust Glasgow, United Kingdom
View Trial Details

Related conditions