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Clinical trial condition

Heterozygous Familial Hypercholesterolemia

Explore clinical trials studying Heterozygous Familial Hypercholesterolemia. Study availability and eligibility vary by location and protocol.

26 public trials 3 recruiting studies
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Heterozygous Familial Hypercholesterolemia trial results

Completed

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

NCT03814187

Conditions
ASCVD, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyslipidemias, +13 more
Locations
  • Research Site 10001-015 Birmingham, Alabama, United States
  • Research Site 10001-138 Foley, Alabama, United States
  • Research Site 10001-113 Huntsville, Alabama, United States
  • Research Site 10001-058 Mobile, Alabama, United States
View all 238 locations
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Completed

Study to Assess the Efficacy and Safety of LIB003 in HeFH Patients on Oral Lipid Therapy Needing Further LDL-C Reduction

NCT04797104

Conditions
Heterozygous Familial Hypercholesterolemia
Locations
  • Metabolic & Atherosclerosis Research Center (MARC) Cincinnati, Ohio, United States
  • Department of Medicine, Hadassah University Hospital Jerusalem, Israel
  • Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel
  • Lipid Clinic, Oslo University Hospital Oslo, Norway
View Trial Details
Completed

Trial Assessing Efficacy, Safety and Tolerability of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition in Paediatric Subjects With Genetic Low-Density Lipoprotein (LDL) Disorders

NCT02392559

Conditions
Dyslipidemias, Heterozygous Familial Hypercholesterolemia, Hypercholesterolemia, +4 more
Locations
  • Research Site Farmington, Connecticut, United States
  • Research Site Wilmington, Delaware, United States
  • Research Site Iowa City, Iowa, United States
  • Research Site Towson, Maryland, United States
View all 66 locations
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Completed

Trial to Evaluate the Effect of Inclisiran Treatment on Low Density Lipoprotein Cholesterol (LDL-C) in Subjects With Heterozygous Familial Hypercholesterolemia (HeFH)

NCT03397121

Conditions
Dyslipidemias, Elevated Cholesterol, Heterozygous Familial Hypercholesterolemia, +5 more
Locations
  • Site 90001-005 Mission Viejo, California, United States
  • Site 90001-001 Newport Beach, California, United States
  • Site 90001-015 Stanford, California, United States
  • Site 90001-047 Boca Raton, Florida, United States
View all 45 locations
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Completed

Open-Label Extension of Study R727-CL-1003 (NCT01266876) to Evaluate the Long-Term Safety and Efficacy of Alirocumab (REGN727) in Participants With Heterozygous Familial Hypercholesterolemia (HeFH)

NCT01576484

Conditions
Dyslipidemias, Heterozygous Familial Hypercholesterolemia, Hypercholesterolemia, +4 more
Locations
  • Mission Viejo, California, United States
  • Newport Beach, California, United States
  • Thousand Oaks, California, United States
  • Miami, Florida, United States
View all 14 locations
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