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Clinical trial condition

Hemophilia A

Explore clinical trials studying Hemophilia A. Study availability and eligibility vary by location and protocol.

600 public trials 74 recruiting studies
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Hemophilia A trial results

Active, Not Recruiting

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12 Months of Age With Hemophilia A Without Inhibitors

NCT04431726

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Phoenix Children's Hospital Phoenix, Arizona, United States
  • Children's Hospital Los Angeles Los Angeles, California, United States
  • University of Colorado Denver, Children's Hospital Aurora, Colorado, United States
  • Tulane University Health Sciences Center New Orleans, Louisiana, United States
View all 32 locations
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Active, Not Recruiting

Study to Test the Safety and How Well Patients With Severe Hemophilia A Respond to Treatment With BAY 2599023 (DTX 201), a Drug Therapy That Delivers a Healthy Version of the Defective Factor VIII Gene Into the Nucleus of Liver Cells Using an Altered, Non-infectious Virus (AAV) as a "Shuttle"

NCT03588299

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +6 more
Locations
  • Arkansas Children's Hospital - Hematology / Oncology Little Rock, Arkansas, United States
  • C.S. Mott Children's Hospital - Hematology / Oncology Ann Arbor, Michigan, United States
  • UW Health Carbone Cancer Center Madison, Wisconsin, United States
  • SHATHD Spec. Hospi. for Active Treatm. of Haematol. Dis. EAD Sofia, Sofia City Province, Bulgaria
View all 13 locations
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Active, Not Recruiting

Evaluating Effectiveness and Long Term Safety of Damoctocog Alfa Pegol in Patients, Who Have Been Diagnosed With Hemophilia A

NCT03932201

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +6 more
Locations
  • South Alabama Medical Science Foundation Mobile, Alabama, United States
  • Banner MD Anderson Cancer Center Phoenix, Arizona, United States
  • University California Davis Davis, California, United States
  • Orthopaedic Hospital DBA Orthopaedic Institute for Children Los Angeles, California, United States
View all 29 locations
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Active, Not Recruiting

Study to Learn More About the Safety of Drug Jivi Over a Long Period of Time in Previously Treated Patients With Hemophilia A (Bleeding Disorder Resulting From a Lack of FVIII) Who Are Receiving Jivi Regularly at Their Treating Doctors to Prevent Bleeding

NCT04461639

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +6 more
Locations
  • Many Locations Multiple Locations, Austria
  • Many Locations Multiple Locations, Germany
  • Many Locations Multiple Locations, Greece
  • Many Locations Multiple Locations, Italy
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Active, Not Recruiting

Early Check: Expanded Screening in Newborns

NCT03655223

Conditions
17 Alpha-Hydroxylase Deficiency, 3-Hydroxy-3-Methylglutaric Aciduria, 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency, +456 more
Locations
  • RTI International Research Triangle Park, North Carolina, United States
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Active, Not Recruiting

Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B

NCT03974113

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Children's Hospital Los Angeles Site Number : 8400002 Los Angeles, California, United States
  • Hackensack University Medical Center- Site Number : 8400008 Hackensack, New Jersey, United States
  • University Hospitals of Cleveland- Site Number : 8400007 Cleveland, Ohio, United States
  • Penn State Milton S. Hershey Medical Center- Site Number : 8400006 Hershey, Pennsylvania, United States
View all 16 locations
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Active, Not Recruiting

A Research Study on How Well Concizumab Works for You if You Have Haemophilia A or B With or Without Inhibitors

NCT05135559

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Rady Childrens Hosp San Diego San Diego, California, United States
  • University of Colorado Hospital Aurora, Colorado, United States
  • Arnold Palmer Children's Hospital Orlando, Florida, United States
  • Nemours Child Orlando Hem/Onc. Orlando, Florida, United States
View all 91 locations
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Active, Not Recruiting

A Clinical Study of Recombinant Human Coagulation Factor VIII for Injection in Patients With Severe Hemophilia A

NCT06297655

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +6 more
Locations
  • Fuyang Hospital Affiliated to Anhui Medical University Fuyang, Anhui, China
  • Anhui Provincial Hospital Hefei, Anhui, China
  • The Second Affiliated Hospital of Chongqing Medical University Chongqing, Chongqing Municipality, China
  • The First Hospital of Lanzhou University Lanzhou, Gansu, China
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Active, Not Recruiting

A Study to Evaluate the Efficacy and Safety of Factor IX Gene Therapy With PF-06838435 in Adult Males With Moderately Severe to Severe Hemophilia B

NCT03861273

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +8 more
Locations
  • UCSF IDS Pharmacy San Francisco, California, United States
  • University of California, San Francisco - Clinical Research Center San Francisco, California, United States
  • University of California, San Francisco - Outpatient Hematology Clinic San Francisco, California, United States
  • The Regents of the University of California, San Francisco campus San Francisco, California, United States
View all 67 locations
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