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Clinical trial condition

Hemoglobinuria, Paroxysmal

Explore clinical trials studying Hemoglobinuria, Paroxysmal. Study availability and eligibility vary by location and protocol.

166 public trials 28 recruiting studies
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Hemoglobinuria, Paroxysmal trial results

Completed

ALXN1210 Versus Eculizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Eculizumab

NCT03056040

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • Research Site Duarte, California, United States
  • Research Site Los Angeles, California, United States
  • Research Site Baltimore, Maryland, United States
  • Research Site Detroit, Michigan, United States
View all 51 locations
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Completed

Study of Efficacy and Safety of Twice Daily Oral Iptacopan (LNP023) in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy

NCT04820530

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • Novartis Investigative Site Beijing, China
  • Novartis Investigative Site Tianjin, China
  • Novartis Investigative Site Tianjin, China
  • Novartis Investigative Site Paris, France
View Trial Details
Completed

Study of Efficacy and Safety of Twice Daily Oral LNP023 in Adult PNH Patients With Residual Anemia Despite Anti-C5 Antibody Treatment

NCT04558918

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • City Of Hope National Med Center City of Hope Medical Center Duarte, California, United States
  • Univ Cali Irvine ALS Neuromuscular Orange, California, United States
  • Augusta University Georgia Patient Treatment Augusta, Georgia, United States
  • Levine Cancer Insitute Carolinas Healthcare System Charlotte, North Carolina, United States
View all 39 locations
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Completed

Ravulizumab Subcutaneous (SC) Versus Ravulizumab Intravenous (IV) in Adults With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Eculizumab

NCT03748823

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • Research Site Los Angeles, California, United States
  • Research Site Liverpool, Australia
  • Research Site Parkville, Australia
  • Research Site Vienna, Austria
View all 51 locations
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Completed

Efficacy, Safety, Pharmacokinetics and Pharmacodynamics Study, Assessing Multiple LNP023 Doses in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria

NCT03896152

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +8 more
Locations
  • Novartis Investigative Site Kota Kinabalu, Sabah, Malaysia
  • Novartis Investigative Site Singapore
  • Novartis Investigative Site Seoul, South Korea
  • Novartis Investigative Site Seoul, South Korea
View Trial Details

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